In "The Indeterministic Character of Evolutionary Theory: No 'Hidden Variables Proof' But No Room for Determinism Either," Brandon and Carson (1996) argue that evolutionary theory is statistical because the processes it describes are fundamentally statistical. In "Is Indeterminism the Source of the Statistical Character of Evolutionary Theory?" Graves, Horan, and Rosenberg (1999) argue in reply that the processes of evolutionary biology are fundamentally deterministic and that the statistical character of evolutionary theory is explained by epistemological rather than ontological considerations. In (...) this paper I focus on the topic of mutation. By focusing on some of the theory and research on this topic from early to late, I show how quantum indeterminism hooks up to point mutations (via tautomeric shifts, proton tunneling, and aqueous thermal motion). I conclude with a few thoughts on some of the wider implications of this topic. (shrink)

I examine the way in which Daniel Dennett (1987, 1995) uses his 'intentional' and 'design' stances to make the claim that intentionality is derived from design. I suggest that Dennett is best understood as attempting to supply an objective, nonintentional, naturalistic rationale for our use of intentional concepts. However, I demonstrate that his overall picture presupposes prior application of the intentional stance in a preconditional, ineliminable,'sense-giving' role. Construed as such, Dennett's account is almost identical to the account of biological teleology (...) offered by Kant in The Critique of Judgement, with the consequence that Dennett's naturalism is untenable. My conclusions lead to doubts concerning the legitimacy of any account attempting to naturalise intentionality by extracting normativity from biology and also point to a novel account of biological function. (shrink)

Kant stresses the regulative status of teleological attributions, but sometimes he seems to treat teleology as a constitutive condition for biology. To clarify this issue, the concept of natural purpose and its role for biology are examined. I suggest that the concept serves an identificatory function: it singles out objects as natural purposes, whereby the special science of biology is constituted. This relative constitutivity of teleology is explicated by means of a distinction of levels: on the object level of biological (...) science, teleology is taken as constitutive, though it is merely regulative on the philosophical meta level. This distinction also concerns the place of Aristotelian teleology in Kant: on the object level, the Aristotelian view is accepted, whereas on the meta level, as agnostic stance is taken concerning teleology. (edited). (shrink)

The impact of Niels Bohr’s 1932 “Light and Life” lecture on Max Delbrück’s lifelong search for a form of “complementarity” in biology is well documented and much discussed, but the precise nature of that influence remains subject to misunderstanding. The standard reading, which sees Delbrück’s transition from physics into biology as inspired by the hope that investigation of biological phenomena might lead to a breakthrough discovery of new laws of physics, is colored much more by Erwin Schrödinger’s What Is Life? (...) than is often acknowledged. Bohr’s view was that teleological and mechanistic descriptions are mutually exclusive yet jointly necessary for an exhaustive understanding of life. Although Delbrück’s approach was empirical and less self‐consciously philosophical, he shared Bohr’s hope that scientific investigation would vindicate the view that at least some aspects of life are not reducible to physico‐chemical terms. (shrink)

Kant -- drawing on his eighteenth-century predecessors -- provided a discerning and powerful characterization of what biologists had to explain in organic form. His difference from the rest is that he opined that was impossible to explain it. Its ’inscrutability’ was intrinsic. The third ’Critique’ essentially proposed the reduction of biology to a kind of prescientific descriptivism, doomed never to attain authentic scientificity. By contrast, for Locke, and ’a fortiori’ for Buffon and his followers, ’intrinsic purposiveness’ was a fact of (...) the matter about concrete biological phenomena; the features of internal self-regulation were hypotheses arising out of actual research practice. The difference comes most vividly to light once we recognize Kant’s distinction of the concept of organism from the concept of life. (edited). (shrink)

We argue that Brandon and Carson's (1996) "The Indeterministic Character of Evolutionary Theory" fails to identify any indeterminism that would require evolutionary theory to be a statistical or probabilistic theory. Specifically, we argue that (1) their demonstration of a mechanism by which quantum indeterminism might "percolate up" to the biological level is irrelevant; (2) their argument that natural selection is indeterministic because it is inextricably connected with drift fails to join the issue with determinism; and (3) their view that experimental (...) methodology in botany assumes indeterminism is both false and incompatible with the commitment to discoverable causal mechanisms underlying biological processes. We remain convinced that the probabilism of the theory of evolution is epistemically, not ontologically, motivated. (shrink)

The article surveys Kant’s treatment of biological teleology in the ’Critique of Judgment’, with special attention to the question of whether the notion of natural teleology is coherent. It argues that our entitlement to regard nature as teleological is not established by the argument of the ’Antinomy’, but rather results from our entitlement to regard the workings of our own cognitive faculties in normative terms. This implies a view of the relation between biological teleology and the representational character of mind (...) which is the reverse of that adopted by naturalistic theorists of mind like Fred Dretske and Ruth Millikan. (shrink)

Vienna's Institute of Experimental Biology, better known as the Vivarium, helped pioneer the quantification of experimental biology from 1903 to 1938. Among its noteable scientists were the director Hans Przibram and his brother Karl , Paul Kammerer, Eugen Steinach, Paul Weiss, and Karl Frisch. The Vivarium's scientists sought to derive laws describing the development of the individual organism and its relationship to the environment. Unlike other contemporary proponents of biological laws, however, these researchers created an explicitly anti-deterministic science. By "laws" (...) they meant statistical regularities or "patterns." They interpreted their experimental results in ways that forged a "third way" between determinism and pure spontaneity, aiming to capture the complexity of the interaction between the organism and its environment. This common feature of their research was made possible by the availability at the Vivarium of the latest in climate-control technology and of methods borrowed from statistical physics. The deeper roots of this search for a "third way" lay, I suggest, in the shared educational, social, and aesthetic experiences of the laboratory's workers. (shrink)

This article is an investigation of parallel themes in Heinrich Hertz's philosophy science and Kant's theory of schemata, symbols and regulative ideas. It is argued that Hertz's "pictures" bears close similarities to Kantian "schemata", that is, they are rules linking concepts to intuitions and provide them with their meaning. Kant's distinction between symbols and schemata is discussed and related to Hertz's three pictures of mechanics. It is argued that Hertz considered his own picture of mechanics (the "hidden mass" picture) as (...) symbolic in a different way than the force and energy pictures. In the final part of the article it is described how Harald Høffding soon after the publication of Hertz's Principles of Mechanics developed a general theory of analogical reasoning, relying on the ideas of Hertz and Kant. (shrink)

This article is an investigation of parallel themes in Heinrich Hertz's philosophy science and Kant's theory of schemata, symbols and regulative ideas. It is argued that Hertz's "pictures" bears close similarities to Kantian "schemata", that is, they are rules linking concepts to intuitions and provide them with their meaning. Kant's distinction between symbols and schemata is discussed and related to Hertz's three pictures of mechanics. It is argued that Hertz considered his own picture of mechanics as symbolic in a different (...) way than the force and energy pictures. In the final part of the article it is described how Harald Høffding soon after the publication of Hertz's Principles of Mechanics developed a general theory of analogical reasoning, relying on the ideas of Hertz and Kant. (shrink)

In this paper we first briefly review Bell's (1964, 1966) Theorem to see how it invalidates any deterministic "hidden variable" account of the apparent indeterminacy of quantum mechanics (QM). Then we show that quantum uncertainty, at the level of DNA mutations, can "percolate" up to have major populational effects. Interesting as this point may be it does not show any autonomous indeterminism of the evolutionary process. In the next two sections we investigate drift and natural selection as the locus of (...) autonomous biological indeterminacy. Here we conclude that the population-level indeterminacy of natural selection and drift are ultimately based on the assumption of a fundamental indeterminacy at the level of the lives and deaths of individual organisms. The following section examines this assumption and defends it from the determinists' attack. Then we show that, even if one rejects the assumption, there is still an important reason why one might think evolutionary theory (ET) is autonomously indeterministic. In the concluding section we contrast the arguments we have mounted against a deterministic hidden variable account of ET with the proof of the impossibility of such an account of QM. (shrink)

The received view on the contributions of the physics community to the birth of molecular biology tends to present the physics community as sharing a basic level consensus on how physics should be brought to bear on biology. I argue, however, that a close examination of the views of three leading physicists involved in the birth of molecular biology, Bohr, Delbrück, and Schrödinger, suggests that there existed fundamental disagreements on how physics should be employed to solve problems in biology even (...) within the physics community. In particular, I focus on how these three figures differed sharply in their assessment of the relevance of complementarity, the potential of chemical methods, and the relative importance of classical physics. In addition, I assess and develop Roll-Hansen’s attempt to conceptualize this history in terms of models of scientific change advanced by Kuhn and Lakatos. Though neither model is fully successful in explaining the divergence of views among these three physicists, I argue that the extent and quality of difference in their views help elucidate and extend some themes that are left opaque in Kuhn’s model. (shrink)

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As the theory of the atom, quantum mechanics is perhaps the most successful theory in the history of science. It enables physicists, chemists, and technicians to calculate and predict the outcome of a vast number of experiments and to create new and advanced technology based on the insight into the behavior of atomic objects. But it is also a theory that challenges our imagination. It seems to violate some fundamental principles of classical physics, principles that eventually have become a part (...) of western common sense since the rise of the modern worldview in the Renaissance. So the aim of any metaphysical interpretation of quantum mechanics is to account for these violations. (shrink)

— Niels Bohr, 19231 “There must be quite definite and clear grounds, why you repeatedly declare that one must interpret observations classically, which lie absolute ly in thei r essenc e. . . . It must belong to your deepest conviction—and I cannot understand on what you base it.”.