This interview reconsiders Donna Haraway’s Cyborg Manifesto 21 years after it was first published. It asks what has become of the three boundary breakdowns around which the Manifesto was structured - those between animals and humans, animal-humans and machines, and the ‘physical and non-physical’. Against this backdrop, this interview examines the connection between the Cyborg Manifesto and Haraway’s more recent writings on companion species, along with what it means to read or write a ‘manifesto’ today. Recent notions of the ‘posthuman’ (...) are also placed into question. (shrink)