A LARGE NUMBER OF PEOPLE, ancient and modern alike, have always found in Socrates what seemed to them a suspicious, if not actually repugnant, aspect. This aspect, to put the point first in crude terms, is his devotion to philosophy, which presupposes an apparently unshakable faith in reason, in the power of understanding to secure goodness, and in the power of goodness to provide us with happiness.

Obsessive-compulsive disorder is a commonly occurring neuropsychiatric condition characterized by bothersome intrusive thoughts and urges that frequently lead to repetitive dysfunctional behaviours such as excessive handwashing. There are well-documented alterations in cerebral function which appear to be closely related to the manifestation of these symptoms. Controlled studies of cognitive-behavioural therapy techniques utilizing the active refocusing of attention away from the intrusive phenomena of OCD and onto adaptive alternative activities have demonstrated both significant improvements in clinical symptoms and systematic changes in (...) the pathological brain circuitry associated with them. Careful investigation of the relationships between the experiential and putative neurophysiological processes involved in these changes can offer useful insights into volitional aspects of cerebral function. (shrink)