Fractured Symmetries: Information and Control Theory Perspectives on Mitochondrial Dysfunction

Acta Biotheoretica 69 (3):277-301 (2020)
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Abstract

Mitochondrial dysfunction underlies a vast array of chronic disorders across the life span. The asymptotic limit theorems of information and control theories, supplemented by symmetry-breaking phase transition arguments adapted from physical theory, give deep insight into canonical mechanisms of cognition and regulation associated with such dysfunction. The probability models studied here can provide a foundation for the development of statistical tools useful in clinical and public health address of those disorders.

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