Ethical questions in human germ-line gene therapy

Abstract

Although the first steps in somatic gene therapy have already taken place, research on human germ-line gene therapy still remains taboo. However, the first protocol aiming to cure defective genes of mitochondria in germ cells has been published recently. Germ-line gene therapy is an entirely new method. Its effects and impact on future generations differ considerably from those of somatic gene therapy.

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Germ-line Gene therapy: Back to basics.Eric T. Juengst - 1991 - Journal of Medicine and Philosophy 16 (6):587-592.
Germ-Line Gene Therapy and the Medical Imperative.Ronald Munson & Lawrence H. Davis - 1992 - Kennedy Institute of Ethics Journal 2 (2):137-158.
Genetic Disorders and the Ethical Status of Germ-Line Gene Therapy.E. M. Berger & B. M. Gert - 1991 - Journal of Medicine and Philosophy 16 (6):667-683.
Should we change the human genome?Torbjörn Tännsjö - 1993 - Theoretical Medicine and Bioethics 14 (3).

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