Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines

Journal of Medical Ethics 46 (12):808-812 (2020)
  Copy   BIBTEX


To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2, some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial.



    Upload a copy of this work     Papers currently archived: 89,491

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Ethical considerations for epidemic vaccine trials.Joshua Teperowski Monrad - 2020 - Journal of Medical Ethics 46 (7):465-469.
Being human in the time of Covid-19.Johann-Albrecht Meylahn - 2020 - HTS Theological Studies 76 (1).
Articulating and responding to uncertainties in clinical research.Benjamin Djulbegovic - 2007 - Journal of Medicine and Philosophy 32 (2):79 – 98.


Added to PP

81 (#186,090)

6 months
5 (#239,721)

Historical graph of downloads
How can I increase my downloads?

Author Profiles

Nir Eyal
Harvard University
Lara Buchak
Princeton University