The Unified Medical Language System and the Gene Ontology: Some critical reflections

In A. Günter, R. Kruse & B. Neumann (eds.), KI 2003: Advances in Artificial Intelligence. Berlin: Springer. pp. 135-148 (2003)
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Abstract

The Unified Medical Language System and the Gene Ontology are among the most widely used terminology resources in the biomedical domain. However, when we evaluate them in the light of simple principles for wellconstructed ontologies we find a number of characteristic inadequacies. Employing the theory of granular partitions, a new approach to the understanding of ontologies and of the relationships ontologies bear to instances in reality, we provide an application of this theory in relation to an example drawn from the context of the pathophysiology of hypertension. This exercise is designed to demonstrate how, by taking ontological principles into account we can create more realistic biomedical ontologies which will also bring advantages in terms of efficiency and robustness of associated software applications.

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Barry Smith
University at Buffalo

References found in this work

Fiat objects.Barry Smith - 2001 - Topoi 20 (2):131-148.
Fiat objects.Barry Smith - 1994 - In Nicola Guarino, Laure Vieu & Simone Pribbenow (eds.), Parts and Wholes: Conceptual Part-Whole Relations and Formal Mereology, 11th European Conference on Artificial Intelligence, Amsterdam, 8 August 1994, Amsterdam:. European Coordinating Committee for Artificial Intelligence. pp. 14-22.
A Theory of Granular Partitions.Thomas Bittner & Barry Smith - 2003 - In Matt Duckham, Michael F. Goodchild & Michael Worboys (eds.), Foundations of Geographic Information Science. London: Taylor & Francis. pp. 117-151.
The ontology of the Gene Ontology.Barry Smith, Jennifer Williams & Steffen Schulze-Kremer - 2003 - In Smith Barry, Williams Jennifer & Schulze-Kremer Steffen (eds.), AMIA 2003 Symposium Proceedings. AMIA. pp. 609-613.
Vague Reference and Approximating Judgements.Thomas Bittner & Barry Smith - 2003 - Spatial Cognition and Computation 3 (2):137–156.

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