Multiple obstacles to gene therapy in the brain

Behavioral and Brain Sciences 18 (1):67-68 (1995)
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Abstract

Neuwelt et al. have proposed gene-transfer experiments utilizing an animal model that offers many important advantages for investigating the feasibility of gene therapy in the human brain. A variety of tissues concerning the viral vector and mode of delivery of the corrective genes need to be resolved, however, before such therapy is scientifically supportable.

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