Asian Bioethics Review 10 (2):133-141 (2018)

With the arrival of new methods of genome editing, especially CRISPR/cas 9, new perspectives on germline interventions have arisen. Supporters of germ line genome editing claim that the procedure could be used as a means of disease prevention. As a possible life-saving therapy, it provides benefits that outweigh its risks. Opponents of GGE claim that the medical and societal risks, especially the use of GGE for genetic enhancement, are too high. In our paper, we analyze the risks and benefits of GGE. We show that the medical risk on an individual level might be reduced by further research in the near future so that they may be outweighed by the benefits. We also show that the societal risks of the procedure, i.e. genetic enhancement, are manageable by establishing a regulative framework before the GGE is implemented. Since the effects of modifying genes for the genepool of a given population are extremely difficult to model, the medical risks on the population level might be too high.
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DOI 10.1007/s41649-018-0056-x
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References found in this work BETA

The Ethics of Germline Gene Editing.Gyngell Christopher, Douglas Thomas & Savulescu Julian - 2017 - Journal of Applied Philosophy 34 (4):498-513.
Ethics and the Risks of Gene Editing.Julian Savulescu & Christopher Gyngell - forthcoming - Ethics in Biology, Engineering and Medicine: An International Journal.
The Medical Case for Gene Editing.Julian Savulescu & Christopher Gyngell - 2015 - Ethics in Biology, Engineering and Medicine: An International Journal 6 (1-2):57-66.
Human Genome Editing.Kevin FitzGerald - 2017 - The National Catholic Bioethics Quarterly 17 (1):107-122.

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