Abstract

This essay seeks a new approach between philosophy and neuroscience inspired by the recent ontological turn to think about one of the affects modulations across the contemporary sociopolitical scenario. In this regard, it theoretically triangulates the appropriation of Spinoza's philosophy by neuroscientist Antonio Damasio and the reception of Damasio's neuroscience by philosopher Catherine Malabou, taking Gilles Deleuze as a connecting point between these perspectives. It proposes to think the concept of destructive plasticity as a metamorphosis in the organism that, shocked by some traumatic event, turns to a new configuration that deactivates its somatic markers and ends up taking a form of disaffection. Finally, it concludes by bringing this figure closer to what Achille Mbembe, taking the death drive as central concept for thinking necropolitics, names as "lumpenradical".