Journal of Medical Ethics 46 (3):199-204 (2020)

Authors
Arthur L. Caplan
New York University
Abstract
Over 115 000 people are waiting for life-saving organ transplants, of whom a small fraction will receive transplants and many others will die while waiting. Existing efforts to expand the number of available organs, including increasing the number of registered donors and procuring organs in uncontrolled environments, are crucial but unlikely to address the shortage in the near future and will not improve donor/recipient compatibility or organ quality. If successful, organ bioengineering can solve the shortage and improve functional outcomes. Studying manufactured organs in animal models has produced valuable data, but is not sufficient to understand viability in humans. Before risking manufactured organ experimentation in living humans, study of bioengineered organs in recently deceased humans would facilitate evaluation of the function of engineered tissues and the complex interactions between the host and the transplanted tissue. Although such studies do not pose risk to human subjects, they pose unique ethical challenges concerning the previous wishes of the deceased, rights of surviving family members, effective operation and fair distribution of medical services, and public transparency. This article investigates the ethical, legal and social considerations in performing engineered organ research on the recently deceased.
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1136/medethics-2019-105674
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy


Upload a copy of this paper     Check publisher's policy     Papers currently archived: 70,079
Through your library

References found in this work BETA

Ethics and Research with Deceased Patients.Mark R. Wicclair - 2008 - Cambridge Quarterly of Healthcare Ethics 17 (1):87-97.
Informed Consent and Research Involving the Newly Dead.Mark R. Wicclair - 2002 - Kennedy Institute of Ethics Journal 12 (4):351-372.

View all 15 references / Add more references

Citations of this work BETA

Somewhere Between Dystopia and Utopia.Jesse Wall - 2020 - Journal of Medical Ethics 46 (3):161-162.

Add more citations

Similar books and articles

The Case Against Conscription of Cadaveric Organs for Transplantation.Walter Glannon - 2008 - Cambridge Quarterly of Healthcare Ethics 17 (3):330-336.
Dealing Death and Retrieving Organs.James Lindemann Nelson - 2009 - Journal of Bioethical Inquiry 6 (3):285-291.
Morality and Marketing Human Organs.Shaheen Borna - 1987 - Journal of Business Ethics 6 (1):37 - 44.
The Dead Donor Rule: Can It Withstand Critical Scrutiny?F. G. Miller, R. D. Truog & D. W. Brock - 2010 - Journal of Medicine and Philosophy 35 (3):299-312.
An "Opting in" Paradigm for Kidney Transplantation.David Steinberg - 2004 - American Journal of Bioethics 4 (4):4 – 14.
Ethical and Legal Aspects of Unrelated Living Donors in Romania.Mihaela Frunza - 2009 - Journal for the Study of Religions and Ideologies 8 (22):3-23.

Analytics

Added to PP index
2019-09-29

Total views
16 ( #665,402 of 2,506,036 )

Recent downloads (6 months)
2 ( #277,268 of 2,506,036 )

How can I increase my downloads?

Downloads

My notes