Maureen A. O’Malley, Ingo Brigandt, Alan C. Love, John W. Crawford, Jack A. Gilbert, Rob Knight, Sandra D. Mitchell & Forest Rohwer
Philosophy of Science 81 (5):811-828 (2014)
Authors | |
Abstract |
Multilevel research strategies characterize contemporary molecular inquiry into biological systems. We outline conceptual, methodological, and explanatory dimensions of these multilevel strategies in microbial ecology, systems biology, protein research, and developmental biology. This review of emerging lines of inquiry in these fields suggests that multilevel research in molecular life sciences has significant implications for philosophical understandings of explanation, modeling, and representation.
|
Keywords | No keywords specified (fix it) |
Categories | (categorize this paper) |
DOI | 10.1086/677889 |
Options |
![]() ![]() ![]() ![]() |
Download options
References found in this work BETA
Explaining the Brain: Mechanisms and the Mosaic Unity of Neuroscience.Carl F. Craver - 2007 - Oxford University Press, Clarendon Press.
Simulation and Similarity: Using Models to Understand the World.Michael Weisberg - 2013 - Oxford University Press.
Re-Engineering Philosophy for Limited Beings: Piecewise Approximations to Reality.William C. Wimsatt - 2007 - Harvard University Press.
Re-Engineering Philosophy for Limited Beings. Piecewise Approximations to Reality.William C. Wimsatt - 2010 - Critica 42 (124):108-117.
View all 27 references / Add more references
Citations of this work BETA
Evolutionary Developmental Biology and the Limits of Philosophical Accounts of Mechanistic Explanation.Ingo Brigandt - 2015 - In P.-A. Braillard & C. Malaterre (eds.), Explanation in Biology: An Enquiry into the Diversity of Explanatory Patterns in the Life Sciences. Springer. pp. 135–173.
Methodological Strategies in Microbiome Research and Their Explanatory Implications.Maureen A. O’Malley & Derek J. Skillings - 2018 - Perspectives on Science 26 (2):239-265.
Scientific Practice in Modeling Diseases: Stances From Cancer Research and Neuropsychiatry.Marta Bertolaso & Raffaella Campaner - 2020 - Journal of Medicine and Philosophy 45 (1):105-128.
Why the Difference Between Explanation and Argument Matters to Science Education.Ingo Brigandt - 2016 - Science & Education 25 (3-4):251-275.
Functionalism, Superduperfunctionalism, and Physicalism: Lessons From Supervenience.Ronald Endicott - 2016 - Synthese 193 (7):2205-2235.
View all 9 citations / Add more citations
Similar books and articles
Dreaming in the Multilevel Framework.Katja Valli - 2011 - Consciousness and Cognition 20 (4):1084-1090.
Philosophies of Particular Biological Research Programs.Ulrich Krohs - 2006 - Biological Theory 1 (2):182-187.
Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation.Ingo Brigandt - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):477-492.
Affirmation of a Developmental Systems Approach to Genetics.Carolyn Tucker Halpern - 2012 - Behavioral and Brain Sciences 35 (5):367-367.
Ins and Outs of Systems Biology Vis-À-Vis Molecular Biology: Continuation or Clear Cut?Philippe De Backer, Danny De Waele & Linda Van Speybroeck - 2010 - Acta Biotheoretica 58 (1):15-49.
Multilevel Causation and the Extended Synthesis.Maximiliano Martínez & Maurizio Esposito - 2014 - Biological Theory 9 (2):209-220.
Approximations, Idealizations and 'Experiments' at the Physics-Biology Interface.Darrell Patrick Rowbottom - 2008 - Studies in History and Philosophy of Biological and Biomedical Sciences 42 (2):145-154.
Local Interaction, Multilevel Selection, and Evolutionary Transitions.Peter Godfrey-Smith - 2006 - Biological Theory 1 (4):372-380.
Plenty of Sex, but No Sexuality in Biology Undergraduate Curricula.Andrew B. Barron, Malin Ah-King & Marie E. Herberstein - 2011 - Bioessays 33 (12):899-902.
Synthetic Biology: Programming Cells for Biomedical Applications.Maximilian Hörner, Nadine Reischmann & Wilfried Weber - 2012 - Perspectives in Biology and Medicine 55 (4):490-502.
Data Without Models Merging with Models Without Data.Ulrich Krohs & Werner Callebaut - 2007 - In Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.), Systems Biology: Philosophical Foundations. Elsevier. pp. 181--213.
Analytics
Added to PP index
2014-11-26
Total views
149 ( #78,409 of 2,505,228 )
Recent downloads (6 months)
2 ( #277,206 of 2,505,228 )
2014-11-26
Total views
149 ( #78,409 of 2,505,228 )
Recent downloads (6 months)
2 ( #277,206 of 2,505,228 )
How can I increase my downloads?
Downloads