A telomerase mutant defective in sister chromatid separation at mitosis

Bioessays 19 (7):557-559 (1997)
  Copy   BIBTEX

Abstract

The telomere is a functional domain of the chromosome, located at the extreme ends, and is essential for normal chromosome stability. Chromosomes lacking telomeres are inherited improperly, and mutations in the telomeric repeat sequences are thought to lead to senescence and possibly to cancer. The molecular mechanisms maintaining chromosomes by telomeres, however, have been unclear. Results recently reported by Kirk et al.(1) offer an insight into new telomerase function. They have identified a novel telomerase mutation that blocks sister chromatid separation in mitosis.

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 92,347

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Some testing of physically defective and of mentally defective children.C. R. McRae - 1926 - Australasian Journal of Philosophy 4 (1):27 – 35.
Meinong's Theory of Defective Objects.Dale Jacquette - 1982 - Grazer Philosophische Studien 15 (1):1-19.
The problem of defective desires.Chris Heathwood - 2005 - Australasian Journal of Philosophy 83 (4):487 – 504.

Analytics

Added to PP
2013-11-23

Downloads
9 (#1,259,819)

6 months
4 (#798,558)

Historical graph of downloads
How can I increase my downloads?