Abstract

This chapter focuses on the dual roleDual role of the physician-researcherPhysician-researcher in clinical trialsClinical trial involving childhood cancerCancer. As the cure rate of childhood cancerCancer has improved from less than 10% in the 1950’s to nearly 80% currently, it is important to note that this is due to dedicated empirical collaborative clinical trialsClinical trial, without which these achievements would not have been possible. However, there are several ethical issues involved in childhood cancerCancer research as the disease is life-threatening. These ethical issues include the tension between the dual roleDual role of being clinician-researcher, recruitment issues, and the translation of clinical research findings into clinical care. Other issues such as proxyProxyconsentConsent and therapeutic misconceptionTherapeutic misconception have been discussed in other chapters.