Perspectives in Biology and Medicine 59 (1):132-146 (2016)

The routine practice of clinical research involving patient-subjects without informed consent prior to 1966 unquestionably was unethical. Does it follow that all clinical research involving competent adult patient-subjects is unethical without informed consent?In his landmark 1966 paper, Henry Beecher noted that of the 50 example studies he had originally compiled in preparation for that paper, only two even mentioned consent, and he observed further that mention of consent is “meaningless unless one knows how fully the patient was informed”. Some of the studies in Beecher’s paper, such as one comparing sulfadiazine with no treatment to assess the complications of streptococcal pharyngitis (when the...
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1353/pbm.2016.0023
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

Upload a copy of this paper     Check publisher's policy     Papers currently archived: 72,607
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

No references found.

Add more references

Citations of this work BETA

Add more citations

Similar books and articles

Empty Ethics: The Problem with Informed Consent.Oonagh Corrigan - 2003 - Sociology of Health & Illness 25 (3):768-792.
Informed Consent in Acute Myocardial Infarction Research.Anne Gammelgaard - 2004 - Journal of Medicine and Philosophy 29 (4):417 – 434.
Pharmacogenetics: The Bioethical Problem of DNA Investment Banking.Oonagh P. Corrigan & Bryn Williams-Jones - 2006 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 37 (3):550-565.


Added to PP index

Total views
22 ( #518,006 of 2,533,643 )

Recent downloads (6 months)
1 ( #389,998 of 2,533,643 )

How can I increase my downloads?


My notes