Perspectives in Biology and Medicine 56 (1):1-17 (2013)
AbstractIn February 2010, the World Medical Association hosted an international symposium on the ethics of placebo controls in clinical trials (WMA 2010). Despite years of debate, ethicists, clinical trialists, and policy makers remain divided over the ethical acceptability of using placebos in research when a proven, effective treatment is available. The protracted nature of this problem is due, at least in part, to a perceived conflict between the opposing demands placed on clinical research by science and ethics. A good, scientifically valid trial, it is argued, must be “assay sensitive,” and without using a placebo control, there can be no guarantee that it is. In this article, we revisit some of the claims made about ..
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Citations of this work
Heuristics and Meta-Heuristics in Scientific Judgement.Spencer Phillips Hey - 2016 - British Journal for the Philosophy of Science 67 (2):471-495.
What Theories Are Tested in Clinical Trials?Spencer Phillips Hey - 2015 - Philosophy of Science 82 (5):1318-1329.
Treatment effectiveness, generalizability, and the explanatory/pragmatic-trial distinction.Steven Tresker - 2022 - Synthese 200 (4):1-29.
Judging Quality and Coordination in Biomarker Diagnostic Development.Spencer Phillips Hey - 2015 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 30 (2):207-227.
Placebo Orthodoxy and the Double Standard of Care in Multinational Clinical Research.Maya J. Goldenberg - 2015 - Theoretical Medicine and Bioethics 36 (1):7-23.
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