Humana Mente 9 (30) (2016)
Abstract |
Proponents of the emerging field of P4 medicine argue that computational integration and analysis of patient-specific “big data” will revolutionize our health care systems, in particular primary care-based disease prevention. While many ambitions remain visionary, steps to personalize medicine are already taken via personalized genomics, mobile health technologies and pilot projects. An important aim of P4 medicine is to enable disease prevention among healthy persons through detection of risk factors. In this paper, we examine the current status of P4 medicine in light of historical and current challenges to predictive and preventive medicine, including overdiagnosis and overtreatment. Moreover, we ask whether it is likely that in silico integration of patient-specific data will be able to better deal such challenges and to turn risk predictions into disease-preventive actions in a wider social context. Given the lack of evidence that P4 medicine can tip the balance between benefits and harms in preventive medicine, we raise concerns about the current promotion of P4 medicine as a solution to the current challenges in public health.
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References found in this work BETA
Big Data: A Revolution That Will Transform How We Live, Work, and Think.[author unknown] - 2013
What Difference Does Quantity Make? On the Epistemology of Big Data in Biology.S. Leonelli - 2014 - Big Data and Society 1 (1).
The New Holism: P4 Systems Medicine and the Medicalization of Health and Life Itself.Henrik Vogt, Bjørn Hofmann & Linn Getz - 2016 - Medicine, Health Care and Philosophy 19 (2):307-323.
Personalized Genomic Medicine and the Rhetoric of Empowerment.Eric T. Juengst, Michael A. Flatt & Richard A. Settersten - 2012 - Hastings Center Report 42 (5):34-40.
View all 12 references / Add more references
Citations of this work BETA
Aging Biomarkers and the Measurement of Health and Risk.Sara Green & Line Hillersdal - 2021 - History and Philosophy of the Life Sciences 43 (1):1-23.
The Limits of Empowerment: How to Reframe the Role of mHealth Tools in the Healthcare Ecosystem.Jessica Morley & Luciano Floridi - 2020 - Science and Engineering Ethics 26 (3):1159-1183.
The prospects of precision psychiatry.Kathryn Tabb & Maël Lemoine - 2021 - Theoretical Medicine and Bioethics 42 (5):193-210.
Personalized Medicine: Evidence of Normativity in its Quantitative Definition of Health.Henrik Vogt, Bjørn Hofmann & Linn Getz - 2016 - Theoretical Medicine and Bioethics 37 (5):401-416.
Neither From Words, nor From Visions: Understanding P-Medicine From Innovative Treatments.Maël Lemoine - 2017 - Lato Sensu, Revue de la Société de Philosophie des Sciences 4 (2).
View all 6 citations / Add more citations
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