Randomized Controlled Trials in Medical AI

Philosophy of Medicine 2 (1) (2021)
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Abstract

Various publications claim that medical AI systems perform as well, or better, than clinical experts. However, there have been very few controlled trials and the quality of existing studies has been called into question. There is growing concern that existing studies overestimate the clinical benefits of AI systems. This has led to calls for more, and higher-quality, randomized controlled trials of medical AI systems. While this a welcome development, AI RCTs raise novel methodological challenges that have seen little discussion. We discuss some of the challenges arising in the context of AI RCTs and make some suggestions for how to meet them.

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Konstantin Genin
Carnegie Mellon University

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