Abstract
In this paper, I present an emerging explanatory framework about ageing and care. In particular, I focus on how, in contrast to most classical accounts of ageing, biomedicine today construes the ageing process as a modifiable trajectory. This framing turns ageing from a stage of inexorable decline into the focus of preventive strategies, harnessing the functional plasticity of the ageing organism. I illustrate this shift by focusing on studies of the demographic dynamics in human population, observations of ageing as an intraspecifically heterogenous phenotype, and the experimental manipulation of longevity, in both model organisms and humans. I suggest that such an explanatory framework about ageing creates the epistemological conditions for the rise of a peculiar form of prevention that does not aim to address a specific condition. Rather it seeks to stall the age-related accumulation of molecular damage and functional deficits, boosting individual resilience against age-related decline. I call this preventive paradigm “ground-state prevention.” While new, ground-state prevention bears conceptual resemblance to forms of medical wisdom prominent in classic Galenic medicine, as well as in the Renaissance period.
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DOI 10.1007/s40656-021-00414-6
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References found in this work BETA

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Ageing and the Goal of Evolution.Justin Garson - 2021 - History and Philosophy of the Life Sciences 43 (1):1-16.

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Rethinking ageing: introduction.Alessandro Blasimme, Giovanni Boniolo & Marco J. Nathan - 2021 - History and Philosophy of the Life Sciences 43 (3):1-8.
Medawar and Hamilton on the selective forces in the evolution of ageing.Stefano Giaimo - 2021 - History and Philosophy of the Life Sciences 43 (4):1-23.

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