A Defense of Syntax-Based Gene Concepts in Postgenomics: Genes as Modular Subroutines in the Master Genomic Program

Philosophy of Science 78 (5):712-723 (2011)
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Abstract

The purpose of this article is to update and defend syntax-based gene concepts. I show how syntax-based concepts can and have been extended to accommodate complex cases of processing and gene expression regulation. In response to difficult cases and causal parity objections, I argue that a syntax-based approach fleshes out a deflationary concept defining genes as genomic sequences and organizational features of the genome contributing to a phenotype. These organizational features are an important part of accepted molecular explanations, provide the theoretical basis for a large number of experimental techniques and practical applications, and play a crucial role in in annotating the genome, deriving predictions and constructing bioinformatics models

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Baetu Tudor
Université du Québec à Trois-Rivières

Citations of this work

Gene.Hans-Jörg Rheinberger - 2008 - Stanford Encyclopedia of Philosophy.
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References found in this work

Genes made molecular.C. Kenneth Waters - 1994 - Philosophy of Science 61 (2):163-185.
Genes in the postgenomic era.Paul E. Griffiths & Karola Stotz - 2006 - Theoretical Medicine and Bioethics 27 (6):499-521.
What is a Gene?Raphael Falk - 1986 - Studies in History and Philosophy of Science Part A 17 (2):133.
Gene.Paul E. Griffiths & Karola Stotz - 2007 - In David L. Hull & Michael Ruse (eds.), The Cambridge Companion to the Philosophy of Biology. New York: Cambridge University Press.

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