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  1. Natural Genome Editing from a Biocommunicative Perspective.Guenther Witzany - 2011 - Biosemiotics 4 (3):349-368.
    Natural genome editing from a biocommunicative perspective is the competent agent-driven generation and integration of meaningful nucleotide sequences into pre-existing genomic content arrangements, and the ability to (re-)combine and (re-)regulate them according to context-dependent (i.e. adaptational) purposes of the host organism. Natural genome editing integrates both natural editing of genetic code and epigenetic marking that determines genetic reading patterns. As agents that edit genetic code and epigenetically mark genomic structures, viral and subviral agents have been suggested because they may be (...)
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  • Evolution of Genetic Information without Error Replication.Guenther Witzany - 2020 - In Theoretical Information Studies. Singapur: pp. 295-319.
    Darwinian evolutionary theory has two key terms, variations and biological selection, which finally lead to survival of the fittest variant. With the rise of molecular genetics, variations were explained as results of error replications out of the genetic master templates. For more than half a century, it has been accepted that new genetic information is mostly derived from random error-based events. But the error replication narrative has problems explaining the sudden emergence of new species, new phenotypic traits, and genome innovations (...)
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  • Life is physics and chemistry and communication.Gunther Witzany - 2015 - In Guenther Witzany (ed.), DNA Habitats and Their RNA Inhabitants. pp. 1-9.
    Manfred Eigen extended Erwin Schroedinger’s concept of “life is physics and chemistry” through the introduction of information theory and cybernetic systems theory into “life is physics and chemistry and information.” Based on this assumption, Eigen developed the concepts of quasispecies and hypercycles, which have been dominant in molecular biology and virology ever since. He insisted that the genetic code is not just used metaphorically: it represents a real natural language.However, the basics of scientific knowledge changed dramatically within the second half (...)
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  • Communication as the Main Characteristic of Life.Guenther Witzany - 2019 - In Vera M. Kolb (ed.), Handbook of Astrobiology. Boca Raton: CrC Press. pp. 91-105.
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  • From Molecular Entities to Competent Agents: Viral Infection-Derived Consortia Act as Natural Genetic Engineers.Günther Witzany - 2012 - In Witzany (ed.), Viruses: Essential Agents of Life. Springer. pp. 407--419.
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  • That is life: communicating RNA networks from viruses and cells in continuous interaction.Guenther Witzany - 2019 - Annals of the New York Academy of Sciences:1-16.
    All the conserved detailed results of evolution stored in DNA must be read, transcribed, and translated via an RNAmediated process. This is required for the development and growth of each individual cell. Thus, all known living organisms fundamentally depend on these RNA-mediated processes. In most cases, they are interconnected with other RNAs and their associated protein complexes and function in a strictly coordinated hierarchy of temporal and spatial steps (i.e., an RNA network). Clearly, all cellular life as we know it (...)
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  • Two genetic codes: Repetitive syntax for active non-coding RNAs; non-repetitive syntax for the DNA archives.Witzany Guenther - 2017 - Communicative and Integrative Biology 10 (2):e1297352-1 - e1297352-12.
    Current knowledge of the RNA world indicates 2 different genetic codes being present throughout the living world. In contrast to non-coding RNAs that are built of repetitive nucleotide syntax, the sequences that serve as templates for proteins share—as main characteristics—a non-repetitive syntax. Whereas non-coding RNAs build groups that serve as regulatory tools in nearly all genetic processes, the coding sections represent the evolutionarily successful function of the genetic information storage medium. This indicates that the differences in their syntax structure are (...)
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