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  1. Philosophy of medicine in 2021.Jeremy R. Simon & Maël Lemoine - 2021 - Theoretical Medicine and Bioethics 42 (5):187-191.
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  • Towards Precision Medicine; a New Biomedical Cosmology.M. W. Vegter - 2018 - Medicine, Health Care and Philosophy 21 (4):443-456.
    Precision Medicine has become a common label for data-intensive and patient-driven biomedical research. Its intended future is reflected in endeavours such as the Precision Medicine Initiative in the USA. This article addresses the question whether it is possible to discern a new ‘medical cosmology’ in Precision Medicine, a concept that was developed by Nicholas Jewson to describe comprehensive transformations involving various dimensions of biomedical knowledge and practice, such as vocabularies, the roles of patients and physicians and the conceptualisation of disease. (...)
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  • Induced Pluripotent Stem Cell-Based Systems for Personalising Epilepsy Treatment: Research Ethics Challenges and New Insights for the Ethics of Personalised Medicine.Mary Jean Walker, Jane Nielsen, Eliza Goddard, Alex Harris & Katrina Hutchison - 2022 - American Journal of Bioethics Neuroscience 13 (2):120-131.
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  • Evidence for Personalised Medicine: Mechanisms, Correlation, and New Kinds of Black Box.Mary Jean Walker, Justin Bourke & Katrina Hutchison - 2019 - Theoretical Medicine and Bioethics 40 (2):103-121.
    Personalised medicine has been discussed as a medical paradigm shift that will improve health while reducing inefficiency and waste. At the same time, it raises new practical, regulatory, and ethical challenges. In this paper, we examine PM strategies epistemologically in order to develop capacities to address these challenges, focusing on a recently proposed strategy for developing patient-specific models from induced pluripotent stem cells so as to make individualised treatment predictions. We compare this strategy to two main PM strategies—stratified medicine and (...)
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  • Aging Biomarkers and the Measurement of Health and Risk.Sara Green & Line Hillersdal - 2021 - History and Philosophy of the Life Sciences 43 (1):1-23.
    Prevention of age-related disorders is increasingly in focus of health policies, and it is hoped that early intervention on processes of deterioration can promote healthier and longer lives. New opportunities to slow down the aging process are emerging with new fields such as personalized nutrition. Data-intensive research has the potential to improve the precision of existing risk factors, e.g., to replace coarse-grained markers such as blood cholesterol with more detailed multivariate biomarkers. In this paper, we follow an attempt to develop (...)
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