Comte argued against the Cartesian conception of the mind that the thinker cannot simultaneously think or perceive and observe itself so doing. Based on insights from cognitive neuroscience, Dehaene has recently given a contemporary answer to Comte’s challenge. He has extended some ideas of Helmholtz on unconscious inferences and argued that we can resolve Comte’s problem by reformulating it in terms of the brain. Since the brain consists of different parts having different functions, it is possible that some parts are (...) involved in observing (they unconsciously process information) while other parts integrate the received information resulting in conscious experiences to which we have access. Dehaene’s answer is criticized and the alternative neo-Aristotelian resolution of Comte’s challenge is discussed. Explanations of blindsight are used to illustrate the differences between the two responses to Comte’s challenge. (shrink)

I present an empirically based argument for the plausibility of misrepresentation as posited by some higher-order theories of consciousness. The argument relies on the assumption that conscious states are generated by processes in the brain. The underlying idea is that if the brain generates conscious states then misrepresentation may occur. The reason for this is that brain states can be corrupted and, accordingly, a conscious state that is at least partly caused by a corrupted brain state may be a misrepresentation. (...) Our body of knowledge from cognitive and behavioral neuroscience lends support to the idea that corruption of neural states is both possible and relatively frequent. If this is the case, I argue, it is plausible that occasionally such corruption may result in misrepresentation. I support this claim by arguing that the most prevalent theoretical alternative to the occurrence of misrepresentation—the so-called no-consciousness reply—seems less supported by our current knowledge in the domain of consciousness and cognition. This way of arguing for misrepresentation is different from other empirically based arguments in the debate because it is a meta-level argument resting on a general premise that most participants in the debate can accept. (shrink)

It appears that consciousness science is progressing soundly, in particular in its search for the neural correlates of consciousness. There are two main approaches to this search, one is content-based (focusing on the contrast between conscious perception of, e.g., faces vs. houses), the other is state-based (focusing on overall conscious states, e.g., the contrast between dreamless sleep vs. the awake state). Methodological and conceptual considerations of a number of concrete studies show that both approaches are problematic: the content-based approach seems (...) to set aside crucial aspects of consciousness; and the state-based approach seems over-inclusive in a way that is hard to rectify without losing sight of the crucial conscious-unconscious contrast. Consequently, the search for the neural correlates of consciousness is in need of new experimental paradigms. (shrink)

Disorders of consciousness include coma, the vegetative state and the minimally conscious state. Such patients are often regarded as unconscious. This has consequences for end of life decisions for these patients: it is much easier to justify withdrawing life support for unconscious than conscious patients. Recent brain imaging research has however suggested that some patients may in fact be conscious.

Current thinking suggests that dissociation could be a significant comorbid diagnosis in a proportion of schizophrenic patients with a history of trauma. This potentially may explain the term “schizophrenia” in its original definition by Bleuler, as influenced by his clinical experience and personal view. Additionally, recent findings suggest a partial overlap between dissociative symptoms and the positive symptoms of schizophrenia, which could be explained by inhibitory deficits. In this context, the process of dissociation could serve as an important conceptual framework (...) for understanding schizophrenia, which is supported by current neuroimaging studies and research of corollary discharges. These data indicate that the original conception of “split mind” may be relevant in an updated context. Finally, recent data suggest that the phenomenal aspects of dissociation and conscious disintegration could be related to underlying disruptions of connectivity patterns and neural integration. (shrink)

This paper discusses the epistemic status of biology from the standpoint of the systemic approach to living systems based on the notion of biological autonomy. This approach aims to provide an understanding of the distinctive character of biological systems and this paper analyses its theoretical and epistemological dimensions. The paper argues that, considered from this perspective, biological systems are examples of emergent phenomena, that the biological domain exhibits special features with respect to other domains, and that biology as a discipline (...) employs some core concepts, such as teleology, function, regulation among others, that are irreducible to those employed in physics and chemistry. It addresses the claim made by Jacques Monod that biology as a science is marginal. It argues that biology is general insofar as it constitutes a paradigmatic example of complexity science, both in terms of how it defines the theoretical object of study and of the epistemology and heuristics employed. As such, biology may provide lessons that can be applied more widely to develop an epistemology of complex systems. (shrink)

In this paper I argue that the prioritization of sensory input by top-down attention is constitutive of and essential to conscious perception. Specifically, I argue that top-down attention is required to provide informational integration at the level of the subject, which can be contrasted with integration at the level of features and objects. Since the informational content of conscious perception requires integration at the level of the subject, top-down attention is necessary for conscious perception as we know it. I present (...) this argument through a theory, which I call the “Standard Theory.” According to this theory, top-down attention brings about subject-level integration for sensory input by prioritizing that input with respect to a subject-level standard. (shrink)

Rafael Malach is currently a professor in the department of Neurobiology at the Weizmann Institute in Israel. His current research is aimed at understanding how the neuronal circuitry in the human brain translates a stream of sensory stimuli into meaningful perception. Rafael Malach received his PhD in physiological optics from UC Berkeley and did his post-doctorate research at MIT. Originally doing research on the organization of neuronal connections in the primate brain, his focus has recently shifted to the study of (...) the human cerebral cortex using fMRI. Professor Malach has begun this research at Massachusetts General Hospital, exploring a new object-related region called the lateral occipital complex. Since then he expanded this research, studying the human visual cortex using a variety of methods, including adaptation paradigms, backward masking, and more recently naturalistic stimuli--all aimed at deciphering the intriguing link between perceptual experience and brain activity. (shrink)