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(Re)defining stem cells

Bioessays 28 (3):301-308 (2006)

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  1. The Boundaries of Development.Lucie Laplane - 2011 - Biological Theory 6 (1):1-3.
    The tacit standard view that development ends once reproductive capacity is acquired (reproductive boundary, or ‘‘RB,’’ thesis) has recently been challenged by biologists and philosophers of biology arguing that development continues until death (death boundary, or ‘‘DB,’’ thesis). The relevance of these two theses is difficult to assess because the fact that there is no precise definition of development makes the determination of its temporal boundaries problematic. Taking into account this difficulty, this article tries to develop a new species-dependent perspective (...)
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  • Systems bioethics and stem cell biology.Jason Scott Robert, Jane Maienschein & Manfred D. Laubichler - 2006 - Journal of Bioethical Inquiry 3 (1-2):19-31.
    The complexities of modern science are not adequately reflected in many bioethical discussions. This is especially problematic in highly contested cases where there is significant pressure to generate clinical applications fast, as in stem cell research. In those cases a more integrated approach to bioethics, which we call systems bioethics, can provide a useful framework to address ethical and policy issues. Much as systems biology brings together different experimental and methodological approaches in an integrative way, systems bioethics integrates aspects of (...)
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  • The Boundaries of Development.Thomas Pradeu, Lucie Laplane, Michel Morange, Antonine Nicoglou & Michel Vervoort - 2011 - Biological Theory 6 (1):1 - 3.
    This special issue of Biological Theory is focused on development; it raises the problem of the temporal and spatial boundaries of development. From a temporal point of view, when does development start and stop? From a spatial point of view, what is it exactly that "develops", and is it possible to delineate clearly the developing entity? This issue explores the possible answers to these questions, and thus sheds light on the definition of development itself.
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  • Blurring nature at its boundaries. Vague phenomena in current stem cell debate.Martin Hähnel - 2017 - Medicine, Health Care and Philosophy 20 (3):373-381.
    This paper illuminates the explanatory role of vagueness und species membership against the background of scientific developments in recent stem cell research. With the help of the Neo-Aristotelian concept of “life form naturalism” ontologically vague entities such as stem cells, all above induced pluripotent stem cells, could be described as necessary constituents for the correct sorting and naming of natural processes and its bearers. Furthermore this specific assessment allows drawing some important ontological and ethical consequences.
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  • The Stem Cell Uncertainty Principle.Melinda Bonnie Fagan - 2013 - Philosophy of Science 80 (5):945-957.
    Stem cells are defined as having capacities for both self-renewal and differentiation. Many different entities satisfy this working definition. I show that this general stem cell concept is relative to a cell lineage, temporal duration, and characters of interest. Experiments specify values for these variables. So claims about stem cells must be understood in terms of experimental methods used to identify them. Furthermore, the stem cell concept imposes evidential constraints on interpretation of experimental results. From these constraints, it follows that (...)
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  • When Traditional Essentialism Fails: Biological Natural Kinds.Robert A. Wilson, Matthew J. Barker & Ingo Brigandt - 2007 - Philosophical Topics 35 (1-2):189-215.
    Essentialism is widely regarded as a mistaken view of biological kinds, such as species. After recounting why (sections 2-3), we provide a brief survey of the chief responses to the “death of essentialism” in the philosophy of biology (section 4). We then develop one of these responses, the claim that biological kinds are homeostatic property clusters (sections 5-6) illustrating this view with several novel examples (section 7). Although this view was first expressed 20 years ago, and has received recent discussion (...)
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  • Psa 2012.-Preprint Volume- - unknown
    These preprints were automatically compiled into a PDF from the collection of papers deposited in PhilSci-Archive in conjunction with the PSA 2012.
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