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  1. Researcher Views on Changes in Personality, Mood, and Behavior in Next-Generation Deep Brain Stimulation.Peter Zuk, Clarissa E. Sanchez, Kristin Kostick-Quenet, Katrina A. Muñoz, Lavina Kalwani, Richa Lavingia, Laura Torgerson, Demetrio Sierra-Mercado, Jill O. Robinson, Stacey Pereira, Simon Outram, Barbara A. Koenig, Amy L. McGuire & Gabriel Lázaro-Muñoz - 2023 - American Journal of Bioethics Neuroscience 14 (3):287-299.
    The literature on deep brain stimulation (DBS) and adaptive DBS (aDBS) raises concerns that these technologies may affect personality, mood, and behavior. We conducted semi-structured interviews with researchers (n = 23) involved in developing next-generation DBS systems, exploring their perspectives on ethics and policy topics including whether DBS/aDBS can cause such changes. The majority of researchers reported being aware of personality, mood, or behavioral (PMB) changes in recipients of DBS/aDBS. Researchers offered varying estimates of the frequency of PMB changes. A (...)
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  • Human Enhancement for the Common Good—Using Neurotechnologies to Improve Eyewitness Memory.Anton Vedder & Laura Klaming - 2010 - American Journal of Bioethics Neuroscience 1 (3):22-33.
    Neurotechnologies that are currently applied to treat a range of neurological and psychiatric diseases were found to have a number of positive side effects on cognitive functioning in healthy individuals. Consequently, these neurotechnologies could in theory be used for cognitive enhancement purposes, for instance, the improvement of eyewitness memory. Improving the process of collecting eyewitness testimony would be of great value and is an example of cognitive enhancement for the common good. In this article, we discuss the epistemological and ethical (...)
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  • On the Significance of the Identity Debate in DBS and the Need of an Inclusive Research Agenda. A Reply to Gilbert, Viana and Ineichen.Anke Snoek, Sanneke de Haan, Maartje Schermer & Dorothee Horstkötter - 2019 - Neuroethics 14 (1):65-74.
    Gilbert et al. argue that the concerns about the influence of Deep Brain Stimulation on – as they lump together – personality, identity, agency, autonomy, authenticity and the self are due to an ethics hype. They argue that there is only a small empirical base for an extended ethics debate. We will critically examine their claims and argue that Gilbert and colleagues do not show that the identity debate in DBS is a bubble, they in fact give very little evidence (...)
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  • Health, Happiness and Human Enhancement—Dealing with Unexpected Effects of Deep Brain Stimulation.Maartje Schermer - 2011 - Neuroethics 6 (3):435-445.
    Deep Brain Stimulation (DBS) is a treatment involving the implantation of electrodes into the brain. Presently, it is used for neurological disorders like Parkinson’s disease, but indications are expanding to psychiatric disorders such as depression, addiction and Obsessive Compulsive Disorder (OCD). Theoretically, it may be possible to use DBS for the enhancement of various mental functions. This article discusses a case of an OCD patient who felt very happy with the DBS treatment, even though her symptoms were not reduced. First, (...)
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  • Stimulating the Self: The Influence of Conceptual Frameworks on Reactions to Deep Brain Stimulation.Giulio Mecacci & W. F. G. Haselager - 2014 - American Journal of Bioethics Neuroscience 5 (4):30-39.
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  • Staying in the Loop: Relational Agency and Identity in Next-Generation DBS for Psychiatry.Sara Goering, Eran Klein, Darin D. Dougherty & Alik S. Widge - 2017 - American Journal of Bioethics Neuroscience 8 (2):59-70.
    In this article, we explore how deep brain stimulation (DBS) devices designed to “close the loop”—to automatically adjust stimulation levels based on computational algorithms—may risk taking the individual agent “out of the loop” of control in areas where (at least apparent) conscious control is a hallmark of our agency. This is of particular concern in the area of psychiatric disorders, where closed-loop DBS is attracting increasing attention as a therapy. Using a relational model of identity and agency, we consider whether (...)
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  • Deep Brain Stimulation Through the “Lens of Agency”: Clarifying Threats to Personal Identity from Neurological Intervention.Eliza Goddard - 2017 - Neuroethics 10 (3):325-335.
    This paper explores the impacts of neurological intervention on selfhood with reference to recipients’ claims about changes to their self-understanding following Deep Brain Stimulation for treatment of Parkinson’s Disease. In the neuroethics literature, patients’ claims such as: “I don’t feel like myself anymore” and “I feel like a machine”, are often understood as expressing threats to identity. In this paper I argue that framing debates in terms of a possible threat to identity—whether for or against the proposition, is mistaken and (...)
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  • Deep Brain Stimulation, Self and Relational Autonomy.Shaun Gallagher - 2018 - Neuroethics 14 (1):31-43.
    Questions about the nature of self and self-consciousness are closely aligned with questions about the nature of autonomy. These concepts have deep roots in traditional philosophical discussions that concern metaphysics, epistemology and ethics. They also have direct relevance to practical considerations about informed consent in medical contexts. In this paper, with reference to understanding specific side effects of deep brain stimulation treatment in cases of, for example, Parkinson’s Disease, Obsessive Compulsive Disorder, and Major Depressive Disorder, I’ll argue that it is (...)
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  • Moral Enhancement: Do Means Matter Morally?Farah Focquaert & Maartje Schermer - 2015 - Neuroethics 8 (2):139-151.
    One of the reasons why moral enhancement may be controversial, is because the advantages of moral enhancement may fall upon society rather than on those who are enhanced. If directed at individuals with certain counter-moral traits it may have direct societal benefits by lowering immoral behavior and increasing public safety, but it is not directly clear if this also benefits the individual in question. In this paper, we will discuss what we consider to be moral enhancement, how different means may (...)
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  • Neuromodulatie en narratieve identiteit.Farah Focquaert - 2018 - Algemeen Nederlands Tijdschrift voor Wijsbegeerte 110 (3):291-313.
    Neuromodulation and narrative identity: the importance of relational autonomyIn this paper, I discuss the impact of psychological and relational changes after neuromodulation for movement- and psychiatric disorders and the need to adequately address the possibility of such changes in clinical contexts. Based on ), ) and ), I outline a relational narrative identity perspective that can inform and support medical-ethical decisions. The narrative identity theory by Marya Schechtman in combination with a focus on the relational aspects that impact and constitute (...)
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  • Situating the self: understanding the effects of deep brain stimulation.Roy Dings & Leon de Bruin - 2016 - Phenomenology and the Cognitive Sciences 15 (2):151-165.
    The article proposes a theoretical model to account for changes in self due to Deep Brain Stimulation. First, we argue that most existing models postulate a very narrow conception of self, and thus fail to capture the full range of potentially relevant DBS-induced changes. Second, building on previous work by Shaun Gallagher, we propose a modified ‘pattern-theory of self’, which provides a richer picture of the possible consequences of DBS treatment.
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  • Situating the self: understanding the effects of deep brain stimulation.Roy Dings & Leon Bruin - 2016 - Phenomenology and the Cognitive Sciences 15 (2):151-165.
    The article proposes a theoretical model to account for changes in self due to Deep Brain Stimulation. First, we argue that most existing models postulate a very narrow conception of self, and thus fail to capture the full range of potentially relevant DBS-induced changes. Second, building on previous work by Shaun Gallagher, we propose a modified ‘pattern-theory of self’, which provides a richer picture of the possible consequences of DBS treatment.
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  • Going Beyond Mind–Body Dualism Requires Revising the Self.Roy Dings & Leon de Bruin - 2014 - American Journal of Bioethics Neuroscience 5 (4):48-50.
    Mecacci and Haselager's (2014) proposal is to reduce maladaptation after DBS treatment by revising the patient's conceptual scheme of the self. We are sympathetic to such an approach, but we want t...
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