Historians have often described embryology and concepts of development in the period around 1800 in terms of “temporalization” or “dynamization”. This paper, in contrast, argues that a central epistemological category in the period was “rhythm”, which played a major role in the establishment of the emerging discipline of biology. I show that Caspar Friedrich Wolff’s epigenetic theory of development was based on a rhythmical notion, namely the hypothesis that organic development occurs as a series of ordered rhythmical repetitions and variations. (...) Presenting Christian Heinrich Pander’s and Karl Ernst von Baer’s theory of germ layers, I argue that Pander and Baer regarded folding as an organizing principle of ontogenesis, and that the principle’s explanatory power stems from their understanding of folding as a rhythmical figuration. In a brief discussion of the notion of rhythm in contemporary music theory, I identify an underlying physiological epistemology in the new musical concept of rhythm around 1800. The paper closes with a more general discussion of the relationship between the rhythmic episteme, conceptions of life, and aesthetic theory at the end of the eighteenth century. (shrink)

RésuméCet article propose d’aborder différemment la longue querelle de la génération, qui divise les ovistes, les spermistes et les partisans de l’épigénèse tout au long des 17e et 18e en Europe. Plutôt que d’en définir les acteurs à partir des publiants, à savoir les médecins ou naturalistes français, anglais et européens qui contredisent les théories ovistes ou spermistes de leurs pairs, je chercherai à poser quelques questions en marge de cette querelle : que reste-t-il d’une querelle une fois qu’elle semble (...) terminée? Comment une querelle est-elle perçue par les contemporains qui auraient un accès fragmentaire à la querelle? Quel est le rôle des querelles scientifiques dans l’éducation des médecins? Je traiterai ces questions en analysant quatre dissertations rédigées par les étudiants en médecine de la Royal Medical Society d’Édimbourg au 18e siècle. (shrink)

ArgumentThis paper aims to understand the emergence of comparative anatomy in the eighteenth century in the Parisian Académie Royale des Sciences. As early as the 1670s, a program centered on animal anatomy was conceived, which was a first attempt to give some autonomy to studies on animals and to link anatomy with natural history, but it declined after 1690. However, a variety of studies on animals was published in theMémoiresof the Académie during the eighteenth century. We propose a descriptive typology (...) of them in order to explore the status of animals and the significance of anatomy in each type, and to determine, in particular, which elements of Perrault's program were passed on at the Académie throughout the century. We discuss the influence of this legacy on the development of comparative anatomy after 1750, especially in Daubenton's work. (shrink)

ArgumentEighteenth-century Montpellerian vitalism and contemporaneous French “vitalist” materialism, exemplified by the medical and biological materialism of La Mettrie and Diderot, differ in some essential aspects from some later forms of vitalism that tended to postulate immaterial vital principles or forces. This article examines the arguments defending the existence of vital properties in living organisms presented in the context of eighteenth-century French materialism. These arguments had recourse to technological metaphors and analogies, mainly clockworks, in order to claim that just as machines (...) can have functional properties which its parts do not possess, so living organisms can, as material entities, also have organic or vital properties which its material parts do not possess. Such arguments, with the help of a healthy dose of epistemological scepticism, tend to strike a balance between two positions concerning the ontology of life which we now tend to label “vitalism” and “emergentism.” Although there is nothing inconsistent in viewing vital properties as emergent, some ambiguity results if one does not draw a clear distinction between properties and functions. The philosophical problems related to these ambiguities are revealed in Diderot's apparent hesitation concerning sentience as “a general property of matter or the product of organization.”. (shrink)

As a historical figure, Lamarck proves a rather difficult subject. His writings give us few explicit leads to his intellectual debts; nor do they present his theories as the outcome of any sustained course of observations or experimental research; and, what is equally frustrating, it is hard to see how his personal development as a scientific theorist was affected by the dramatic political and social upheavals of the period, in which he took an active and lively interest. And so, with (...) his importance for later writers much clearer than his relationship to those of his own and earlier ages, historians have repeatedly interpreted his works as prophetic of doctrines developed more fully by subsequent generations. No less surprisingly, this facile tactic has provoked a reaction; we have been offered Lamarck as a Stoic, a romantic, harking back to Heraclitus. (shrink)

Reconstructions of Romantic-era life science in general, and epigenesis in particular, frequently take the Kantian logic of autotelic “self-organization” as their primary reference point. I argue in this essay that the Kantian conceptual rubric hinders our historical and theoretical understanding of epigenesis, Romantic and otherwise. Neither a neutral gloss on epigenesis, nor separable from the epistemological deflation of biological knowledge that has received intensive scrutiny in the history and philosophy of science, Kant’s heuristics of autonomous “self-organization” in the third Critique (...) amount to the strategic capture of epigenesis from nature, for thought, in thought’s critical transcendence of nature. This essay looks to Jean-Baptiste Lamarck and his English contemporary Erasmus Darwin to begin to reconstruct the rigorously materialist, naturalist, and empiricist theories of epigenesis marginalized by Kantian argumentation. As theorists of environmental and social collaboration in the ontogeny of viable forms, Lamarck and Darwin illuminate features of our own epigenetic turn obscured by the rhetoric of “self-organization,” allowing us to glimpse an alternative Romantic genealogy of the biological present. (shrink)

. In aid of understanding mechanistic explanation and its limits in the 17th century, I examine the views of Pierre Sylvain Régis on generation. Régis departs from Descartes' theories on one key point. Living things, though they do not differ in nature from nonliving things, and are, as Descartes said, machines, are directly created by God, who forms the seeds of all living things at creation. Preformationism gives Régis not only a means of accounting for seeds and for specific differences (...) among living things, but also a basis for attributing purposes to them, and thus for defining health and disease in soulless creatures. (shrink)

À l'orée du xvme siècle, Wilhelm Gottfried Leibniz et Friedrich Hoffmann critiquent la théorie médicale de Georg Ernst Stahl. Ils trient le vrai du faux. En l'occurrence, ils reprennent à leur compte la définition stahlienne de la respiration en l'extirpant de ses fondements animistes pour la placer dans une épistémologie soumise au principe de raison suffisante et au modèle mécanique. La découverte stahlienne consiste à penser la respiration comme ventilation calorifique à l'encontre de la conception antique ; les iatromécaniciens reconnaissent (...) la justesse de la notion stahlienne, ils essaient alors de la transposer dans un modèle mécanique de la ventilation. Cette reprise dans un contexte épistémologique différent implique une analyse critique de l'idée de découverte« vraie» dans son contenu, mais « fausse» dans ses hypothèses. Elle oblige en outre à interroger l'épistémologie de la connaissance médicale, en tant que science et thérapeutique, et ses liens avec les autres disciplines. En effet, si Leibniz philosophe et Hoffmann médecin prennent au sérieux la théorie animiste de Stahl, c'est que l'importance de ses découvertes met en cause les fondements de la médecine. (shrink)

ArgumentAt the end of the seventeenth and beginning of the eighteenth century, ageing was specifically a medical issue. Indeed, on the one hand, ageing is a normal process of living; on the other hand, old age often entails specific pathologies. Is it really possible to dissociate old age from pathology? If so, how can we think of old age and explain both the necessity and the normality of it? If not, what is the cause of this dysfunction? Modern medical controversies (...) argue along the lines of the respective partisans ofiatromecanism, empirical medicine, and animist medicine. Furthermore, it progressively appears that the issue of aging must also be addressed within the social field, where old age is affected by sanitary, economic, and strategic conditions. Indeed, doctors, economists, and philosophers even tried to assess old age quantitatively with new methods of arithmetic. Thus, in this paper, we want to draw what constitutes the systems of knowledge of old age as a medical category located at the borderlines between epistemological, practical, and social challenges. (shrink)

This paper seeks to characterize how the study of nutrition processes contributed to revisit the problem of vital organization in the late eighteenth century. It argues that focusing on nutrition leads to reformulate the problem of the relation between life and organization in terms of processes, rather than static or given structures. This nutrition-centered approach to life amounts to acknowledge the specific strategic role nutrition played in the development of a materialist approach to the generation of vital organization. The paper (...) proposes a clarification of the multiple meanings of the concept of organization in the context of Enlightenment physiology and nascent biology, before focusing on the century long analogy between nutrition and generation. It shows how, by contrasting different uses of this analogy, nutrition was employed as a key vital phenomenon in the development of epigenetic theories of generation, i.e. how a nutritive modeling of generation was used in the undermining of preformationism. To this purpose I contrast two seemingly opposite theories of generation, Buffon’s and Bonnet’s, and show that despite the obvious metaphysical discontent, their views of generation share a common mechanical conceptual frame in which nutrition is conflated with growth and repair. I then turn to the role nutrition played in the epigenetic conception of generation in C. F. Wolff’s embryology and analyze this rival understanding of nutrition as an organizing process. (shrink)

Many physicians, anatomists and natural philosophers engaged in attempts to map the seat of the soul during the so-called Scientific Revolution of the European seventeenth century. The history of these efforts needs to be told in light of the puzzlement bred by today's strides in the neurological sciences. The accounts discussed here, most centrally by Nicolaus Steno, Claude Perrault and Thomas Willis, betray the acknowledgement that a gap remained between observable form, on the one hand, and motor and sensory functions, (...) on the other. Observation yielded information about form, but did not guarantee a constant correlation with presumed function, while the mechanisms of sense and movement did not fit in with accounts of action and cognition whose purpose was to place the connection between active body and willful, conscious soul onto a descriptive rather than metaphysical plane. Teleology was now no longer a helpful tool in the disciplines of anatomy and physiology; the consequences of this are still with us. (shrink)