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  1. A New Ethical Framework for Assessing the Unique Challenges of Fetal Therapy Trials: Response to Commentaries.Saskia Hendriks, Christine Grady, David Wasserman, David Wendler, Diana W. Bianchi & Benjamin Berkman - 2022 - American Journal of Bioethics 22 (3):45-61.
    New fetal therapies offer important prospects for improving health. However, having to consider both the fetus and the pregnant woman makes the risk–benefit analysis of fetal therapy trials challenging. Regulatory guidance is limited, and proposed ethical frameworks are overly restrictive or permissive. We propose a new ethical framework for fetal therapy research. First, we argue that considering only biomedical benefits fails to capture all relevant interests. Thus, we endorse expanding the considered benefits to include evidence-based psychosocial effects of fetal therapies. (...)
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  • Fetal Repair of Open Neural Tube Defects: Ethical, Legal, and Social Issues.Julia A. E. Radic, Judy Illes & Patrick J. Mcdonald - 2019 - Cambridge Quarterly of Healthcare Ethics 28 (3):476-487.
    :Open neural tube defects or myelomeningoceles are a common congenital condition caused by failure of closure of the neural tube early in gestation, leading to a number of neurologic sequelae including paralysis, hindbrain herniation, hydrocephalus and neurogenic bowel and bladder dysfunction. Traditionally, the condition was treated by closure of the defect postnatally but a recently completed randomized controlled trial of prenatal versus postnatal closure demonstrated improved neurologic outcomes in the prenatal closure group. Fetal surgery, or more precisely maternal-fetal surgery, raises (...)
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