Facts about moral disagreement and human evolution have both been said to exclude the possibility of moral knowledge, but the question of how these challenges interact has largely gone unaddressed. The paper aims to present and defend a novel version of the evolutionary “debunking” argument for moral skepticism that appeals to both types of considerations. This argument has several advantages compared to more familiar versions. The standard debunking strategy is to argue that evolutionary accounts of moral beliefs generate skeptical implications (...) because they attribute those beliefs to factors that are unrelated to their truth. That strategy is vulnerable to “third-factor” responses, which invoke first-order moral claims to challenge the assumption that Darwinian factors and the moral truths are really unrelated in that way. In contrast, our version is immune to those responses, as it does not proceed via assumptions about how Darwinian factors relate to the moral facts. Instead, it focuses on what evolutionary accounts of moral beliefs have to say about the fact that people often reach divergent moral beliefs. The argument thereby illustrates how the debunking strategy can join forces with the argument from moral disagreement. The combination of those strategies presents, we think, a challenge that is more formidable than when they are considered separately. (shrink)