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  1. Imaging the brain: visualising “pathological entities”? Searching for reliable protocols within psychiatry and their impact on the understanding of psychiatric diseases. [REVIEW]Lara Huber - 2008 - Poiesis and Praxis 6 (1-2):27-41.
    Given that visualisations via medical imaging have tremendously increased over the last decades, the overall presence of colour-coded brain slices generated on the basis of functional imaging, i.e. neuroimaging techniques, have led to the assumption of so-called kinds of brains or cognitive profiles that might be especially related to non-healthy humans affected by neurological, neuropsychological or psychiatric syndromes or disorders. In clinical contexts especially, one must consider that visualisations through medical imaging are suggestive in a twofold way. Imaging data not (...)
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  • Shaping Vulnerable Bodies at the Thin Boundary between Environment and Organism: Skin, DNA Repair, and a Genealogy of DNA Care Strategies.Alexander von Schwerin - 2015 - Science in Context 28 (3):427-464.
    ArgumentThis paper brings together the history of risk and the history of DNA repair, a biological phenomenon that emerged as a research field in between molecular biology, genetics, and radiation research in the 1960s. The case of xeroderma pigmentosum (XP), an inherited hypersensitivity to UV light and, hence, a disposition to skin cancer will be the starting point to argue that, in the 1970s and 1980s, DNA repair became entangled in the creation of new models of the human body at (...)
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  • Locating Rods and Cones: Microscopic Investigations of the Retina in Mid-Nineteenth-Century Berlin and Würzburg.Jutta Schickore - 2000 - Science in Context 13 (1):137-152.
    The ArgumentThis paper is concerned with the diversity of microscopic research in nineteenth-century life sciences. It examines how two researchers, Ernst Wilhelm Brücke and Heinrich Müller, investigated the structure and function of the retina. They did so in significantly different ways, thereby developing quite different accounts of this organ and its role in the process of vision. Both investigators were carrying out microscopic investigations, both were particularly concerned with interpreting their findings in terms of physiological function, and both employed the (...)
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  • The animal model of human disease as a core concept of medical research: Historical cases, failures, and some epistemological considerations.Volker Roelcke - 2022 - Science in Context 35 (2):173-197.
    ArgumentThis article uses four historical case studies to address epistemological issues related to the animal model of human diseases and its use in medical research on human diseases. The knowledge derived from animal models is widely assumed to be highly valid and predictive of reactions by human organisms. In this contribution, I use three significant historical cases of failure (ca. 1890, 1960, 2006), and a closer look at the emergence of the concept around 1860/70, to elucidate core assumptions related to (...)
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