http://dx.doi.org/10.5007/1808-1711.2008v12n1p49 The aim of this article is to offer a rejoinder to an argument against scientific realism put forward by van Fraassen, based on theoretical considerations regarding microphysics. At a certain stage of his general attack to scientific realism, van Fraassen argues, in contrast to what realists typically hold, that empirical regularities should sometimes be regarded as “brute facts”, which do not ask for explanation in terms of deeper, unobservable mechanisms. The argument from microphysics formulated by van Fraassen is based (...) on the claim that in microphysics the demand for explanation leads to a demand for the so-called hidden-variable theories, which “runs contrary to at least one major school of thought in twentieth-century physics”. It is shown here that this argument does not represent an insurmountable obstacle to scientific realism, not even when a series of important theoretical and experimental results against hidden-variable theories — and not merely a conflict with a certain school of thought—is taken into account. (shrink)