In this paper, we examine the use of the term ‘life’ in the debates within and about synthetic biology. We review different positions within these debates, focusing on the historical background, the constructive epistemology of laboratory research and the pros and cons of metaphorical speech. We argue that ‘life’ is used as buzzword, as folk concept, and as theoretical concept in inhomogeneous ways. Extending beyond the review of the significant literature, we also argue that ‘life’ can be understood as aBurstwordin (...) two concrete senses. Firstly, terms such as life easily turn into fuzzy, foggy and buzzy clouds of nonsense, if their use is not appropriately reflected. In these cases, the semantic orientation is detonated. This is theBurstword Icharacteristic of the concept of ‘life’ that we reveal for its unclear terminological use. Secondly, and in contrast toBurstword I, we show that the concept of ‘life’ can be used in a methodologically controlled way. We call this kind of useBurstword II. Here the concept of ‘life’ fulfils the function of expanding an inadequately narrow disciplinary or conceptual focus in different discursive contexts. In this second sense, ‘life’ receives an important operational function, for instance as a transdisciplinary research principle. It turns out that the innovative function and paradigm-changing power of metaphorical speech belong here as well. Finally, we illustrate three ethically relevant examples that show how ‘life’ can be applied asBurstword IIin the context of synthetic biology. (shrink)

Philosophy may relate to interdisciplinarity in two distinct ways On the one hand, philosophy may play an auxiliary role in the process of interdisciplinarity, typically through conceptual analysis, in the understanding that the disciplines themselves are the main epistemic players. This version of the relationship I characterise as ‘normal’ because it captures the more common pattern of the relationship, which in turn reflects an acceptance of the division of organized inquiry into disciplines. On the other hand, philosophy may be itself (...) the site for the production of interdisciplinary knowledge, understood as a kind of second-order understanding of reality that transcends the sort of knowledge that the disciplines provide, left to their own devices. This is my own position, which I dub ‘deviant’ and to which most of this article is devoted. I begin by relating the two types of interdisciplinarity to the organization of inquiry, especially their respective attitudes to the history of science. Underlying the two types are contrasting notions of what constitutes the ‘efficient’ pursuit of knowledge. This difference is further explored in terms of the organization of the university. The normal/deviant distinction was already marked in the institution’s medieval origins in terms of the difference between Doctors and Masters, respectively, an artefact of which remains in the postgraduate/undergraduate degree distinction. In the context of the history of the university, the prospects for deviant interdisciplinarity were greatest from the early sixteenth to the early nineteenth century—the period called ‘early modern’ in the philosophy curriculum. Towards the end of that period, due to Kant and the generation of idealists who followed him, philosophy was briefly the privileged site for deviant interdisciplinarity. After Hegel’s death, the mantle of deviant interdisciplinarity increasingly passed to some version of ‘biology’. I explore the ‘Natur-’ and ‘Geisteswissenschaft’ versions of that post-philosophical vision, which continue to co-exist within today’s biological science. I then briefly examine the chequered reputation of Jean-Baptiste Lamarck, someone who exemplified the promise and perils of deviant interdisciplinarity over the past 200 years. I conclude with an Epilogue that considers contemporary efforts to engage philosophy in interdisciplinary work, invoking William James as an exemplar. (shrink)

We extend the concept that life is an informational phenomenon, at every level of organisation, from molecules to the global ecological system. According to this thesis: living is information processing, in which memory is maintained by both molecular states and ecological states as well as the more obvious nucleic acid coding; this information processing has one overall function—to perpetuate itself; and the processing method is filtration of, and synthesis of, information at lower levels to appear at higher levels in complex (...) systems . We show how information patterns, are united by the creation of mutual context, generating persistent consequences, to result in ‘functional information’. This constructive process forms arbitrarily large complexes of information, the combined effects of which include the functions of life. Molecules and simple organisms have already been measured in terms of functional information content; we show how quantification may be extended to each level of organisation up to the ecological. In terms of a computer analogy, life is both the data and the program and its biochemical structure is the way the information is embodied. This idea supports the seamless integration of life at all scales with the physical universe. The innovation reported here is essentially to integrate these ideas, basing information on the ‘general definition’ of information, rather than simply the statistics of information, thereby explaining how functional information operates throughout life. (shrink)

In this paper, I discuss the concept of complexity. I show that the principle of natural selection as acting on complexity gives a solution to the problem of reconciling the seemingly contradictory notion of generally increasing complexity and the observation that most species don’t follow such a trend. I suggest the process of evolution to be illustrated by means of a schematic diagram of complexity versus time, interpreted as a form of the Tree of Life. The suggested model implies that (...) complexity is cumulatively increasing, giving evolution a direction, an arrow of time, thus also implying that the latest emerging species will be the one with the highest level of complexity. Since the human species is the last species evolved in the evolutionary process seen at large, this means that we are the species with the highest complexity. The model implies that the human species constitutes an integral part of organic evolution, yet rendering us the exclusive status as the species of the highest complexity. (shrink)

We discuss a less known aspect of Feynman’s multifaceted scientific work, centered about his interest in molecular biology, which came out around 1959 and lasted for several years. After a quick historical reconstruction about the birth of molecular biology, we focus on Feynman’s work on genetics with Robert S. Edgar in the laboratory of Max Delbruck, which was later quoted by Francis Crick and others in relevant papers, as well as in Feynman’s lectures given at the Hughes Aircraft Company on (...) biology, organic chemistry and microbiology, whose notes taken by the attendee John Neer are available. An intriguing perspective comes out about one of the most interesting scientists of the XX century. (shrink)

The possession of degree of autonomy in living beings: In the numerous attempts to define the concept of life, the use of prefixes like “self”, “auto” appears recurrently. This shows the fundamental importance attached to autonomy among the living beings. The author first analyzes the various types and degrees of autonomy, beginning from some contemporary thinkers, like Jonas, Morin, Varela, Davies, Wandschneider; and afterwards, the various types of systemic autonomy are compared with the four systemic levels of contemporary biological theories. (...) The dependent autonomy of morphogenesis relative to the genetic level is presented as a paradigm of systemic autonomy. Stratified emergence and relative containment of systemic levels and their causal interdependencies, reveal life’s tendency to increase and maximize autonomous levels. A study of individual autonomy is also presented and developed around the concepts of feedback and feed-forwards, homeostasis, motor and feeding autonomy, to develop more fully towards the emancipation and exploratory autonomies, as self-determinacies. These types of higher autonomies are the result of several properties, especially the equipotentiality related to attractors exhibiting flat spread basins of attraction. These properties are shaped by the lower functional levels as logistical granting for autonomous decision-making capability at the higher level. The author follows Jonas’ theory affirming the intrinsic tendency of living systems to produce increasingly refined autonomies, whose supreme analog degree is found in human freedom. So, autonomy is presented as an analog concept applicable to all living, biological and spiritual. (shrink)

The connection between brain and mind is an important scientific and philosophical question that we are still far from completely understanding. A crucial point to our work is noticing that thermodynamics provides a convenient framework to model brain activity, whereas cognition can be modeled in information-theoretical terms. In fact, several models have been proposed so far from both approaches. A second critical remark is the existence of deep theoretical connections between thermodynamics and information theory. In fact, some well-known authors claim (...) that the laws of thermodynamics are nothing but principles in information theory. Unlike in physics or chemistry, a formalization of the relationship between information and energy is currently lacking in neuroscience. In this paper we propose a framework to connect physical brain and cognitive models by means of the theoretical connections between information theory and thermodynamics. Ultimately, this article aims at providing further insight on the formal relationship between cognition and neural activity. (shrink)

Functionalism in the philosophy of mind is here criticized from the perspective of a more naturalistic and less compromising form of materialism. Parallels are explored between the problem of cognitive activity and the somewhat more settled problem of vital activity. The lessons drawn suggest that functionalism in the philosophy of mind may be both counterproductive as a research strategy, and false as a substantive position.

Introductory Abstract Philosophers of science, in the course of making a sharp distinction between the tasks of the philosopher and those of the scientist, have pointed to the possibility of an empirical science of induction. A comparative psychology of knowledge processes is offered as one aspect of this potential enterprise. From fragments of such a psychology, methodological suggestions are drawn relevant to several chronic problems in the social sciences, including the publication of negative results from novel explorations, the operational diagnosis (...) of dispositions, the status of aggregates of persons as social entities, and the validation of psychological tests. (shrink)

The article will bring some theoretical considerations to be applied to a study of the goal‐structure of human life.One of the theoretical questions in which this study is interested concerns the origin of the different goals and goal‐changes during life. One of the central questions is how goal‐setting and goal‐changes are brought about, what factors are responsible, what mechanisms come into play.The material of the planned research study will be selected individual and interview cases whose goal‐development and goal‐changes will be (...) examined and interpreted.The present study is to survey some of the concepts and theoretical considerations to be applied in the study of individual's goal‐setting, toward a general theory of goal‐setting in human life. (shrink)

The biological sciences study (bio)complex living systems. Research directed at the mechanistic explanation of the "live" state truly requires a pluralist research program, i.e. BioComplexity research. The program should apply multiple intra-level and inter-level theories and methodologies. We substantiate this thesis with analysis of BioComplexity: metabolic and modular control analysis of metabolic pathways, emergence of oscillations, and the analysis of the functioning of glycolysis.

The issue of biotechnology has been chosen in the MIRRORS project in order to analyze the sometimes uneasy relationship between science and society. After analyzing the situation of biotechnology regarding the GMO debate in Spain, France and Italy during a previous MIRRORS Workshop (This MIRRORS Workshop is entitled European Policies and Knowledge Society, held in Catania on December 15th 2008, during the which the undersigned, Anna Benedetta Francese and Cinzia Rizza discussed three papers about this topic [see the MIRRORS website (...) www.mirrors-project.it]), in this essay I have tried to tackle the relationship science–society, focalizing my attention on the epistemological and methodological problems behind the biotechnology debate that are often not clearly expressed, remaining mainly tacitly presupposed. I will take as a starting point some questions about the role of science in society and about the way science is used by policy makers in decision-making processes. These questions are fundamental in order to analyze (and possibly to propose salvation strategies) the existing problems of the relationship between science and society which has assumed, especially nowadays, more conflictual aspects. Our Research Team firmly holds that it is not possible to tackle this topic without an in-depth discussion of the most significant epistemological questions regarding research, discussions, and methods of biotechnology. (shrink)

We discuss the meaning of “being alive” and “being dead.” Our primary aim is to pave the way for a sound and accurate ethical debate concerning these two concepts. In particular, we analyze a metabolic approach and a genetic one and discuss the reasons for their failure to constitute a good starting point for successive debates. We argue that any ethical or social discussion of topics involving life and death must introduce cultural constructs such as, on the one hand, the (...) concept of clinical death and, on the other hand, the concept of existence. We argue that these two cultural constructs, although consistent with biomedical knowledge, cannot be ontologically grounded in it. To conclude, we apply our findings to the case of human embryos. (shrink)

The following paper will present some outcomes of research into the topic of clairvoyance in a European context and the depiction of the spiritual in film in order to suggest that a cultural analysis of the perception of the angelic imaginary can offer insights into the interrelation between the subject areas of cinema and consciousness. This research on clairvoyance began in 1997 as part of an interdisciplinary study arising out of the disciplines of Cultural Anthropology and Film Theory at the (...) University of Amsterdam: it focused on the phenomenon of the clairvoyant perception of angels and compared this with the treatment of the spiritual in film. One major outcome of this study reveals a significant correspondence between the general cinema experience and the clairvoyants' perception of apparitions: both could be adequately described as multi-sensorial experiences reaching beyond the audio-visual perception into a stimulation of an internal affection (in the Bergsonian use of the term) imbricated with thought, memory and association, embracing the importance of the often underrated sensations of touch, smell and emotions. What follows will summarize these insights and situate them within a broader theoretical context, in which the work of Henri Bergson will be revisited through the subsequent insights of Gilles Deleuze in order to re-evaluate Deleuze's contribution and place my own research within an interdisciplinary framework of Philosophy, Film Studies and Cultural Anthropology. (shrink)

Language, through the discrete nature of linguistic names and strictly determined grammatical rules, creates absolute, “quantized”, sharply separated “facts” within the external world that is continuous, “fuzzy” and relational in its essence. Therefore, it is similar, in some important sense, to magic, which attributes causal and creative power to magical words and formulas. On the one hand, language increases greatly the effectiveness of the processes of thinking and interpersonal communication, yet, on the other hand, it determines and distorts to a (...) large extent the picture of the world created within the mind. The relatively smallest (but still significant) magical admixture is present in science, because of its relatively reliable methodology, while the largest is found in religion and a large part of philosophy. The magical nature of language also manifests itself in logic and mathematics that refer to ill determined, fuzzy objects, sets and relations in the real world. The meaning of linguistic names is based on the conceptual network—an epiphenomenon (continuous in its essence) of the neural network—where interactions between particular concepts are based on the relation of connotation. The names and formulas of language correspond to these concepts which are best separated and determined. A direct relation of denotation between the elements of language and “facts” of the world is an illusion. While we cannot dispense with language because of its immense usefulness, we must remember about its “fact-creating” nature and influence on our thought and cognitive processes. The picture of the reality created as the result of them is to a large extent formed and deformed by the nature of language, and not by the “immanent” properties of the world in itself. (shrink)

Summary Based on Clausius’ phrasing of a “transformational content” and the resulting 2nd law of thermodynamics, I demonstrated that Gilbert Simondon’s On the Mode of Existence of Technical Objects is historically situated at the threshold of understanding open systems thermodynamics and the related concepts of balance. Furthermore, I showed that Gestalt theory, as represented by Wolfgang Köhler, at least reproduced, if not partially anticipated or even prepared this development of 20th century thinking. Finally, I gave some short examples of how (...) Simondon applied the figure/ground distinction to human perception, memory, and a general theory of becoming and I introduced his proposal to analyse “the grounds” just as thoroughly as the laws of figuration. (shrink)

Today there are two major theoretical frameworks in biology. One is the ‘chemical paradigm’, the idea that life is an extremely complex form of chemistry. The other is the ‘information paradigm’, the view that life is not just ‘chemistry’ but ‘chemistry-plus-information’. This implies the existence of a fundamental difference between information and chemistry, a conclusion that is strongly supported by the fact that information and information-based-processes like heredity and natural selection simply do not exist in the world of chemistry. Against (...) this conclusion, the supporters of the chemical paradigm have pointed out that information processes are no different from chemical processes because they are both described by the same physical quantities. They may appear different, but this is only because they take place in extremely complex systems. According to the chemical paradigm, in other words, biological information is but a shortcut term that we use to avoid long descriptions of countless chemical reactions. It is intuitively appealing, but it does not represent a new ontological entity. It is merely a derived construct, a linguistic metaphor. The supporters of the information paradigm insist that information is a real and fundamental entity of Nature, but have not been able to prove this point. The result is that the chemical view has not been abandoned and the two paradigms are both coexisting today. Here it is shown that an alternative does exist and is a third theoretical framework that is referred to as the ‘code paradigm’. The key point is that we need to introduce in biology not only the concept of information but also that of meaning because any code is based on meaning and a genetic code does exist in every cell. The third paradigm is the view that organic information and organic meaning exist in every living system because they are the inevitable results of the processes of copying and coding that produce genes and proteins. Their true nature has eluded us for a long time because they are nominable entities, i.e., objective and reproducible observables that can be described only by naming their components in their natural order. They have also eluded us because nominable entities exist only in artifacts and biologists have not yet come to terms with the idea that life is artifact making. This is the idea that life arose from matter and yet it is fundamentally different from it because inanimate matter is made of spontaneous structures whereas life is made of manufactured objects. It will be shown, furthermore, that the existence of information and meaning in living systems is documented by the standard procedures of science. We do not have to abandon the scientific method in order to introduce meaning in biology. All we need is a science that becomes fully aware of the existence of organic codes in Nature. (shrink)

Biosemiotics is the synthesis of biology and semiotics, and its main purpose is to show that semiosis is a fundamental component of life, i.e., that signs and meaning exist in all living systems. This idea started circulating in the 1960s and was proposed independently from enquires taking place at both ends of the Scala Naturae. At the molecular end it was expressed by Howard Pattee’s analysis of the genetic code, whereas at the human end it took the form of Thomas (...) Sebeok’s investigation into the biological roots of culture. Other proposals appeared in the years that followed and gave origin to different theoretical frameworks, or different schools, of biosemiotics. They are: (1) the physical biosemiotics of Howard Pattee and its extension in Darwinian biosemiotics by Howard Pattee and by Terrence Deacon, (2) the zoosemiotics proposed by Thomas Sebeok and its extension in sign biosemiotics developed by Thomas Sebeok and by Jesper Hoffmeyer, (3) the code biosemiotics of Marcello Barbieri and (4) the hermeneutic biosemiotics of Anton Markoš. The differences that exist between the schools are a consequence of their different models of semiosis, but that is only the tip of the iceberg. In reality they go much deeper and concern the very nature of the new discipline. Is biosemiotics only a new way of looking at the known facts of biology or does it predict new facts? Does biosemiotics consist of testable hypotheses? Does it add anything to the history of life and to our understanding of evolution? These are the major issues of the young discipline, and the purpose of the present paper is to illustrate them by describing the origin and the historical development of its main schools. (shrink)

Can there be higher level laws of nature even though everything is reducible to the fundamental laws of physics? The computer science notion of level of abstraction explains how there can be.

Morphological Computation is based on the observation that biological systems seem to carry out relevant computations with their morphology (physical body) in order to successfully interact with their environments. This can be observed in a whole range of systems and at many different scales. It has been studied in animals – e.g., while running, the functionality of coping with impact and slight unevenness in the ground is "delivered" by the shape of the legs and the damped elasticity of the muscle-tendon (...) system – and plants, but it has also been observed at the cellular and even at the molecular level – as seen, for example, in spontaneous self-assembly. The concept of morphological computation has served as an inspirational resource to build bio-inspired robots, design novel approaches for support systems in health care, implement computation with natural systems, but also in art and architecture. As a consequence, the field is highly interdisciplinary, which is also nicely reflected in the wide range of authors that are featured in this e-book. We have contributions from robotics, mechanical engineering, health, architecture, biology, philosophy, and others. (shrink)

Extract from Hofstadter's revew in Bulletin of American Mathematical Society : http://www.ams.org/journals/bull/1980-02-02/S0273-0979-1980-14752-7/S0273-0979-1980-14752-7.pdf -/- "Aaron Sloman is a man who is convinced that most philosophers and many other students of mind are in dire need of being convinced that there has been a revolution in that field happening right under their noses, and that they had better quickly inform themselves. The revolution is called "Artificial Intelligence" (Al)-and Sloman attempts to impart to others the "enlighten- ment" which he clearly regrets not having (...) experienced earlier himself. Being somewhat of a convert, Sloman is a zealous campaigner for his point of view. Now a Reader in Cognitive Science at Sussex, he began his academic career in more orthodox philosophy and, by exposure to linguistics and AI, came to feel that all approaches to mind which ignore AI are missing the boat. I agree with him, and I am glad that he has written this provocative book. The tone of Sloman's book can be gotten across by this quotation (p. 5): "I am prepared to go so far as to say that within a few years, if there remain any philosophers who are not familiar with some of the main developments in artificial intelligence, it will be fair to accuse them of professional incom- petence, and that to teach courses in philosophy of mind, epistemology, aesthetics, philosophy of science, philosophy of language, ethics, metaphysics, and other main areas of philosophy, without discussing the relevant aspects of artificial intelligence will be as irresponsible as giving a degree course in physics which includes no quantum theory." -/- (The author now regrets the extreme polemical tone of the book.). (shrink)

A general definition of consciousness is: ‘consciousness is a mental aspect of a system or a process, which is a conscious experience, a conscious function, or both depending on the context’, where the term context refers to metaphysical views, constraints, specific aims, and so on. One of the aspects of visual consciousness is the visual subjective experience (SE) or the first person experience that occurs/emerges in the visual neural-network of thalamocortical system (which includes dorsal and ventral visual pathways and frontal (...) cortex) during dynamic interactions among widely distributed neuronal groups. In this article, however, consciousness and SE are interchangeably used unless noted. Consciousness can be either access (reportable) or phenomenal consciousness. For access consciousness, the interactions are between feed forward stimulus dependent signals and fronto-parietal feedback attentional signals. The necessary ingredients for access (reportable) consciousness are (i) wakefulness, (ii) reentrant interactions among neural populations, (iii) fronto-parietal and thalamic-reticular-nucleus attentional signals that modulate consciousness, (iv) working memory that retains information for consciousness, (v) stimulus at or above threshold level, and (vi) neural-network proto-experiences (PEs) that are superposed SEs embedded in a neural-network. Attention and the ability to report are not necessary for phenomenal consciousness. The neural source for the arousal system is the ascending reticular activating system in the brain stem, which brings the thalamocortical neural networks to wakeful state as a baseline for consciousness to occur. Reentrant interactions among neural populations bind stimulus attributes (such as location and features) and entail consciousness. Attention could be the results of reentry and competitive interactions, and modulates the stimulus related feed forward signal and consciousness. The ‘sources’ of attention may be thalamic reticular nucleus for bottom-up or frontal cortex for top-down direction. The ‘target’ of visual attention is ‘V4/V8/VO’ for Red-Green (R-G) channel. The neural correlates of the psychophysical entity R-G channel appear to be ‘V4/V8/VO’-neural-network (retina → LGN ↔ V1 ↔ V2 ↔ ‘V4/V8/VO’, and areas for attention, memory, and wakefulness). The psychophysical Red-Green Channel, its neurophysiological correlates V4/V8/VO-neural-network, and related experience (such as redness) are integrated. The dual-aspect-dual-mode PE-SE framework (Vimal, J Integr Neurosci 7:49–73, 2008) was used to address the explanatory gap problem of materialism. Neural-network and related SEs are the results of the co-evolution and co-development of the material aspect (mass, charge, spin, force, quanta, and space-time) and the mental aspect of fundamental particles (strings or elementary particles (fermions and bosons)). Their mental aspects are considered as the carriers of superposed multiple possible experiences (SEs/PEs) in unexpressed form. These possibilities are actualized when neural-networks are formed via neural Darwinism, and a specific SE is selected by a matching process when the necessary ingredients of consciousness/SE are satisfied. A simple experimental design is suggested to address the necessary and sufficient attributes of consciousness. (shrink)

Many mechanisms, functions and structures of life have been unraveled. However, the fundamental driving force that propelled chemical evolution and led to life has remained obscure. The second law of thermodynamics, written as an equation of motion, reveals that elemental abiotic matter evolves from the equilibrium via chemical reactions that couple to external energy towards complex biotic non-equilibrium systems. Each time a new mechanism of energy transduction emerges, e.g., by random variation in syntheses, evolution prompts by punctuation and settles to (...) a stasis when the accessed free energy has been consumed. The evolutionary course towards an increasingly larger energy transduction system accumulates a diversity of energy transduction mechanisms, i.e. species. The rate of entropy increase is identified as the fitness criterion among the diverse mechanisms, which places the theory of evolution by natural selection on the fundamental thermodynamic principle with no demarcation line between inanimate and animate. (shrink)

This paper deals with the question of agency and intentionality in the context of the free-energy principle. The free-energy principle is a system-theoretic framework for understanding living self-organizing systems and how they relate to their environments. I will first sketch the main philosophical positions in the literature: a rationalist Helmholtzian interpretation (Hohwy 2013; Clark 2013), a cybernetic interpretation (Seth 2015b) and the enactive affordance-based interpretation (Bruineberg and Rietveld 2014; Bruineberg et al. 2016) and will then show how agency and intentionality (...) are construed differently on these different philosophical interpretations. I will then argue that a purely Helmholtzian is limited, in that it can account only account for agency in the context of perceptual inference. The cybernetic account cannot give a full account of action, since purposiveness is accounted for only to the extent that it pertains to the control of homeostatic essential variables. I will then argue that the enactive affordance-based account attempts to provide broader account of purposive action without presupposing goals and intentions coming from outside of the theory. In the second part of the paper, I will discuss how each of these three interpretations conceives of the sense agency and intentionality in different ways. (shrink)

A common approach in biosemiotics suggests that semiosis (any activity or process that involves signs) is a natural process embedded in evolution, which entails the production of meaningful processes. As Pattee has argued, a closer look at living systems shows that semiosis is closely related to a very specific and highly functional context of selected constraints. Symbolic control consists in 1) instituting a friction on the novelty, variability and randomness of life processes 2) allowing survival value at all levels of (...) biological organization and 3) enabling self-organization. Then it would be the network of semiotic controls to actually playing a pivotal role in biological organization and evolution. (shrink)

In this paper, I use the comparison between human beings and intelligent machines to shed light on the concept of teleology. What characterizes human beings and distinguishes them from a robot capable of achieving complex objectives? In the first place, by stipulating that what characterizes human beings are mental states, I consider the mark of the mental. A smart robot probably has no consciousness but we might have reason for doubt while interacting with it. And a smart robot shows intentionality. (...) I focus on the type of naturalized intentionality that is at stake here. Then I go back to the traditional idea of teleology, and to the scientific criticism of it, through the question of the kind of purposes that artificial intelligence (AI) may set itself. Husserl's basic idea of teleology therefore serves to have an authoritative term of comparison and to introduce the intuitive difference between human beings and intelligent machines based on the homo pictor thought experiment proposed by Jonas. My conclusion is that a specific finalism, understood in a non-criterial sense, is what qualifies the human being and differentiates the latter (for now) from smart robots. (shrink)

Perhaps there has been no greater opportunity than in this “VOLUME FIFTEEN of our Death And Anti-Death set of anthologies” to write about how might think about life and how to avoid death. There are two reasons to discuss “life”, the first being enhancing our understanding of who we are and why we may be here in the Universe. The second is more practical: how humans meet the physical challenges brought about by the way they have interacted with their environment. (...) Many persons discussing “life” beg the question about what “life” is. Surely, when one discusses how to overcome its opposite, death, they are not referring to another “living” thing such as a plant. There seems to be a commonality, though, and it is this commonality is one needing elaboration. It ostensibly seems to be the boundary condition separating what is completely passive (inert) from what attempts to maintain its integrity, as well as fulfilling other conditions we think “life” has. In our present discussion, there will be a reminder that it by no means has been unequivocally established what life really is by placing quotes around the word, namely, “life”. Consider it a tag representing a bundle of philosophical ideas that will be unpacked in this paper. (shrink)

ve r since the appearance of Ontogeny and Phylogeny a decade ago, Stephen Jay Gould has continued to delight and inform a wide spectrum of readers and, in doing so, to defy C.P. Snow's lament about the "two cultures" of the sciences and the humanities. Gould's monthly column in Natural History magazine, published under the heading "This View of Life," has led to a series of highly praised volumes of essays—Ever Since Darwin (1977), The Panda's Thumb (1980), Hen's Teeth and (...) Horse's Toes (1983), and most recently The Flamingo's Smile (1985). In addition, Gould's The Mismeasure of Man (1981), which won the National Book Critics' Circle Award, analyzed the questionable character of intelligence testing and emphasized the many personal and cultural biases that have led researchers astray in this field. Given the sheer amount of Gould's publications, which include numerous scientific publications as well, Gould's readers have been kept busy indeed absorbing his prodigious output. (shrink)

This brief systems back-casting of statistical post portems on the US economy documents the quantitative heuristic errors of financial decision-making; the need for sound monetary reform is explained.

The present article is devoted to the problem which is debated actively to-day, namely whether Greek poleis and the Roman Republic were early states or they represented a specific type of stateless societies. In particular, Moshe Berent examines this problem by the example of Athens in his contribution to this volume. He arrives at the conclusion that Athens was a stateless society. However, I am of the opinion that this conclusion is wrong: and I believe that Athens and Rome were (...) early states. Therefore the present article is in many respects a direct discussion with Berent (as well as with other supporters of this idea). (shrink)

Context: W. R. Ashby’s work on homeostasis as the basic mechanism underlying all kinds of physiological as well as cognitive functions has aroused renewed interest in cognitive science and related disciplines. Researchers have successfully incorporated some of Ashby’s technical results, such as ultrastability, into modern frameworks (e.g., CTRNN networks). Problem: The recovery of Ashby’s technical contributions has left in the background Ashby’s far more controversial non-technical views, according to which homeostatic adaptation to the environment governs all aspects of all forms (...) of life. This thesis entails that life is fundamentally “heteronomous” and it is conceptually at odds with the autopoiesis framework adopted by Ashby’s recent defenders as well as with the primacy of autonomy in human life that most of the Western philosophical tradition upholds. The paper argues that the use of computer simulations focused on the more conceptual aspects of Ashby’s thought may help us recover, extend and consequently assess an overall view of life as heteronomy. Method: The paper discusses some computer simulations of Ashby’s original electro-mechanical device (the homeostat) that implement his techniques (double-feedback loops and random parameter-switching). Results: First simulation results show that even though Ashby’s claims about homeostatic adaptivity need to be slightly weakened, his overall results are confirmed, thereby suggesting that an extension to virtual robots engaged in minimal cognitive tasks may be successful. Implications: The paper shows that a fuller incorporation of Ashby’s original results into recent cognitive science research may trigger a philosophical and technical reevaluation of the traditional distinction between heteronomous and autonomous behavior. Constructivist content: The research outlined in the paper supports an extended constructionist perspective in which agency as autonomy plays a more limited role. (shrink)

Fundamental to Computer Science is the distinction between abstractions and implementations. When that distinction is applied to various philosophical questions it yields the following conclusions. -/- • EMERGENCE. It isn’t as mysterious as it’s made out to be; the possibility of strong emergence is not a threat to science. -/- • INTERACTIONS BETWEEN HIGHER-LEVEL ENTITIES. Physical interaction among higher-level entities is illusory. Abstract interactions are the source of emergence, new domains of knowledge, and complex systems. -/- • PHYSICS and the (...) SPECIAL SCIENCES. The new domains of knowledge derived from abstract interactions are the basis of the autonomy of the special sciences. -/- • DOWNWARD CAUSATION. It’s a zombie idea that should have a stake put through its heart and be replaced by downward entailment. (shrink)

Current medical genetics research is dominated by a single theory that supports the Human Genome Project rationale. This thesis investigates this and several alternative hypotheses and the ethical context related to their development. Firstly, the hypotheses are discussed in detail followed by a subsection in which research evidence based on each hypothesis is cited. Secondly, these medical genetics hypotheses are situated within the contemporary medical paradigm. To conclude, the thesis examines in depth the ethical and practical implications of medical genetics (...) research. A framework of analysis of scientific responsibility is used to explore these implications. Scientific responsibility, as presented in this thesis, is a process consisting of three steps: scientific discourse; the development of the nature of scientific responsibility; and, effective criticism. Once scientific responsibility is defined, the term is applied specifically to the field of medical genetics research. (shrink)

This paper explores some of the factors that make complex systems complex. We first examine the history of complex systems. It was Aristotle’s insight that how elements are joined together helps determine the properties of the resulting whole. We find (a) that scientific reductionism does not provide a sufficient explanation; (b) that to understand complex systems, one must identify and trace energy flows; and (c) that disproportionate causality, including global tipping points, are all around us. Disproportionate causality results from the (...) wide availability of energy stores. We discuss three categories of emergent phenomena—static, dynamic, and adaptive—and recommend retiring the term emergent, except perhaps as a synonym for creative. Finally, we find that virtually all communication is stigmergic. (shrink)

This paper discussses various concepts of biological information with particular attention being paid to genetic information.