Engineers must deal with risks and uncertainties as a part of their professional work and, in particular, uncertainties are inherent to engineering models. Models play a central role in engineering. Models often represent an abstract and idealized version of the mathematical properties of a target. Using models, engineers can investigate and acquire understanding of how an object or phenomenon will perform under specified conditions. This paper defines the different stages of the modeling process in engineering, classifies the various sources of (...) uncertainty that arise in each stage, and discusses the categories into which these uncertainties fall. The paper then considers the way uncertainty and modeling are approached in science and the criteria for evaluating scientific hypotheses, in order to highlight the very different criteria appropriate for the development of models and the treatment of the inherent uncertainties in engineering. Finally, the paper puts forward nine guidelines for the treatment of uncertainty in engineering modeling. (shrink)

It can be argued that there is an ethical requirement to classify correctly what is known and what is unknown in decision situations, especially in the context of biomedicine when risks and benefits have to be assessed. This is because other methods for assessing potential harms and benefits, decision logics and/or ethical principles may apply depending on the kind or degree of uncertainty. However, it is necessary to identify and describe the various epistemic states of uncertainty relevant to such estimates (...) in the first place. Therefore, this paper aims to develop a category system of different epistemic states of uncertainty which, although not exclusively, is primarily intended to be applied to early clinical trials. It is formed on the basis—and various combinations—of three dimensions of uncertainty that represent certain parts of incomplete knowledge: outcome (type of event), probability (of outcome) and evaluation (assessment of outcome). Furthermore, it is argued that uncertainty can arise from three different sources (the structure of the object of research, the state of the evidence, or individual handling of the research and already existing knowledge). The categories developed are applied to actual examples from gene therapy and genome editing to illustrate that they can be helpful for a more precise definition of the respective uncertainties, especially in the context of risk–benefit assessment. The categories allow a differentiated perspective of decision-making situations from the point of view of incomplete knowledge in general, but particularly, for example, in early clinical research, and may thereby support a more acceptable ethical assessment of potential harms and benefits. (shrink)

The primary aim of this article is to develop and defend a conceptual analysis of safety. The article begins by considering two previous analyses of safety in terms of risk acceptability. It is argued that these analyses fail because the notion of risk acceptability is more subjective than safety, as risk acceptability takes into account potential benefits in a way that safety does not. A distinction is then made between two different kinds of safety—safety qua cause and safety qua recipient—and (...) both are defined in terms of the probability of a loss of value, though the relationship between safety and the probability of loss varies in each case. It is then shown that although this analysis is less subjective than the previously considered analyses, subjectivity can still enter into judgments of safety via the notions of probability and value. In the final section of this article, it is argued that the difference between safety and risk acceptability is important because it corresponds in significant ways to the difference between consequentialist and deontological moral viewpoints. (shrink)

The philosophical–ethical literature and the public debate on autonomous vehicles have been obsessed with ethical issues related to crashing. In this article, these discussions, including more empirical investigations, will be critically assessed. It is argued that a related and more pressing issue is questions concerning safety. For example, what should we require from autonomous vehicles when it comes to safety? What do we mean by ‘safety’? How do we measure it? In response to these questions, the article will present a (...) foundation for a continued discussion on these issues and an argument for why discussions about safety should be prioritized over ethical concerns related to crashing. (shrink)

A common objection to the precautionary principle is that it is irrational. I argue that this objection goes beyond the often-discussed claim that the principle is incoherent. Instead, I argue, exp...

This doctoral thesis analyses the concept of risk and how it functions as an organizing principle of discourse, paying close attention to actual linguistic practice. Article 1 analyses the concepts of risk, safety and security and their relations based on corpus data. Lexical, grammatical and semantic contexts of the nouns risk, safety and security, and the adjectives risky, safe and secure are analysed and compared. Similarities and differences are observed, suggesting partial synonymy between safety and security and semantic opposition to (...) risk. The findings both support and contrast theoretical assumptions about these concepts in the literature. Article 2 analyses the concepts of risk and danger and their relation based on corpus data. Frame semantics is used to explore the assumptions of the sociologist Niklas Luhmann that the risk concept presupposes decision-making, while the concept of danger does not. Findings partly support and partly contradict this assumption. Article 3 analyses how newspapers represent risk and causality. Two theories are used: media framing and the philosopher John Mackie’s account of causality. A central finding of the study is that risks are “framed” with respect to causality in several ways. Furthermore, newspaper reporting on risk and causality vary in complexity. In some articles, risks are presented without causal explanations, while in other articles, risks are presented as results from complex causal conditions. Considering newspaper reporting on an aggregated overall level, complex schemas of causal explanations emerge. Article 4 analyses how phenomena referred to by the term nano are represented as risks in Swedish newspaper reporting. Theoretically, the relational theory of risk and frame semantics are used. Five main groups of nano-risks are identified based on the risk object of the article: nanotechnology; nanotechnology and its artefacts ; nanoparticles, without referring to nanotechnology; non-nanotechnological nanoparticles ; and nanotechnology and nanorobots. Various patterns are explored within each group, concerning, for example, what is considered to be at stake in relation to these risk objects, and under what conditions. It is concluded that Swedish patterns of newspaper reporting on nano-risks follow international trends, influenced by scientific assessment, as well as science fiction. Article 5 analyses the construction and negotiation of risk in the Swedish controversy over the use of antibacterial silver in health care and consumer products. The controversy involves several actors: print and television news media, Government and parliament, governmental agencies, municipalities, non-government organisations, and companies. In the controversy, antibacterial silver is claimed to be a risk object that negatively affects health, the environment, and sewage treatment industry. In contrast, such claims are denied. Antibacterial silver is even associated with the benefit of mitigating risk objects that threaten health and the environment. In other words, both sides of the controversy invoke health and the environment as objects at risk. Three strategies organising risk communication are identified: representation of silver as a risk to health and the environment; denial of such representations; and benefit association, where silver is construed to mitigate risks to health and the environment. (shrink)

Practical methods are introduced for the construction of definitions, both for philosophical purposes and for uses in other disciplines. The structural and contentual requirements on definitions are clarified. It is emphasized that the development of a definition should begin with careful choice of a primary definiendum, followed by the selection of appropriate variables for the definition. Two methods are proposed for the construction of the definiens, the case list method and the method of successive improvements. Four classes of concepts are (...) discussed that are particularly difficult to define: vague concepts, value-laden concepts, controversial concepts, and inconsistent concepts. (shrink)