That one person's modus ponens is another's modus tollens is the bane of philosophy because it strips many philosophical arguments of their persuasive force. The problem is that philosophical arguments become mere pantomemes: arguments that are reasonable to resist simply by denying the conclusion. Appeals to proof, intuition, evidence, and truth fail to alleviate the problem. Two broad strategies, however, do help in certain circumstances: an appeal to normal informal standards of what is reasonable (nisowir) and argument by interpretation. The (...) method of explication features prominently in both strategies, and the paper extends this method to apply to nisowir, introducing the concept of canonical explication. The paper illustrates the two strategies with examples of arguments from formal epistemology and suggests that an appeal to nisowir might help to defend against philosophical scepticism by shifting the burden of proof to the sceptic. (shrink)

Systems medicine is a promising new paradigm for discovering associations, causal relationships and mechanisms in medicine. But it faces some tough challenges that arise from the use of big data: in particular, the problem of how to integrate evidence and the problem of how to structure the development of models. I argue that objective Bayesian models offer one way of tackling the evidence integration problem. I also offer a general methodology for structuring the development of models, within which the objective (...) Bayesian approach fits rather naturally. (shrink)

The relationship between machine learning and the philosophy of science can be classed as a dynamic interaction: a mutually beneficial connection between two autonomous fields that changes direction over time. I discuss the nature of this interaction and give a case study highlighting interactions between research on Bayesian networks in machine learning and research on causality and probability in the philosophy of science.

Reichenbach’s ‘principle of the common cause’ is a foundational assumption of some important recent contributions to quantitative social science methodology but no similar principle appears in econometrics. Angrist et al. has argued that the principle is necessary for instrumental variables methods in econometrics, and Angrist Krueger builds a framework using it that he proposes as a means of resolving an important methodological dispute among econometricians. Through analysis of instrumental variables methods and the issue of multicollinearity, we aim to show that (...) the relationship of the principle to econometric methods is more nuanced than implied by previous work but nevertheless may make a valuable contribution to the coherence and validity of existing methods. (shrink)

An otherwise lawlike generalisation hedged by a ceteris paribus (CP) clause qualifies as a law of nature, if the CP clause can be substituted with a set of conditions derived from the multivariate regression model used to interpret the empirical data in support of the gen- eralisation. Three studies in human biology that use regression analysis are surveyed, showing that standard objections to cashing out CP clauses in this way—based on alleged vagueness, vacuity, or lack of testability—do not apply. CP (...) laws also cannot be said to be simply false due to the indefinitely many conditions not explicitly stated in their associated model: scientific CP clauses imply that these are, given the evidence, not nomically relevant. (shrink)

Bayesian reasoning has been applied formally to statistical inference, machine learning and analysing scientific method. Here I apply it informally to more common forms of inference, namely natural language arguments. I analyse a variety of traditional fallacies, deductive, inductive and causal, and find more merit in them than is generally acknowledged. Bayesian principles provide a framework for understanding ordinary arguments which is well worth developing.

This essay explains what the Causal Markov Condition says and defends the condition from the many criticisms that have been launched against it. Although we are skeptical about some of the applications of the Causal Markov Condition, we argue that it is implicit in the view that causes can be used to manipulate their effects and that it cannot be surrendered without surrendering this view of causation.

A pervasive feature of the sciences, particularly the applied sciences, is an experimental focus on a few (often only one) possible causal connections. At the same time, scientists often advance and apply relatively broad models that incorporate many different causal mechanisms. We are naturally led to ask whether there are normative rules for integrating multiple local experimental conclusions into models covering many additional variables. In this paper, we provide a positive answer to this question by developing several inference rules that (...) use local causal models to place constraints on the integrated model, given quite general assumptions. We also demonstrate the practical value of these rules by applying them to a case study from ecology. Experimental scope in applied sciences Fusing the results of experiments A concrete example of the inference rules Application to a case study. (shrink)

Reichenbach's 'principle of the common cause' is a foundational assumption of some important recent contributions to quantitative social science methodology but no similar principle appears in econometrics. Reiss (2005) has argued that the principle is necessary for instrumental variables methods in econometrics, and Pearl (2009) builds a framework using it that he proposes as a means of resolving an important methodological dispute among econometricians. We aim to show, through analysis of the main problem instrumental variables methods are used to resolve, (...) that the relationship of the principle to econometric methods is more nuanced than implied by previous work, but nevertheless may make a valuable contribution to the coherence and validity of existing methods. (shrink)