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  1. Psychiatric comorbidity: fact or artifact?Hanna M. van Loo & Jan-Willem Romeijn - 2015 - Theoretical Medicine and Bioethics 36 (1):41-60.
    The frequent occurrence of comorbidity has brought about an extensive theoretical debate in psychiatry. Why are the rates of psychiatric comorbidity so high and what are their implications for the ontological and epistemological status of comorbid psychiatric diseases? Current explanations focus either on classification choices or on causal ties between disorders. Based on empirical and philosophical arguments, we propose a conventionalist interpretation of psychiatric comorbidity instead. We argue that a conventionalist approach fits well with research and clinical practice and resolves (...)
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  • Crossing the Threshold: An Epigenetic Alternative to Dimensional Accounts of Mental Disorders.Davide Serpico & Valentina Petrolini - forthcoming - British Journal for the Philosophy of Science.
    Recent trends in psychiatry involve a transition from categorical to dimensional frameworks, in which the boundary between health and pathology is understood as a difference in degree rather than as a difference in kind. A major tenet of dimensional approaches is that no qualitative distinction can be made between health and pathology. As a consequence, these approaches tend to characterize such a threshold as pragmatic or conventional in nature. However, dimensional approaches to psychopathology raise several epistemological and ontological issues. First, (...)
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  • The Challenges Raised by Comorbidity in Psychiatric Research: The Case of Autism.Valentina Petrolini & Agustín Vicente - 2022 - Philosophical Psychology 1:1-28.
    Despite several criticisms surrounding the DSM classification in psychiatry, a significant bulk of research on mental conditions still operates according to two core assumptions: a) homogeneity, that is the idea that mental conditions are sufficiently homogeneous to justify generalization; b) additive comorbidity, that is the idea that the coexistence of multiple conditions in the same individual can be interpreted as additive. In this paper we take autism research as a case study to show that, despite a plethora of criticism, psychiatric (...)
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  • The challenges raised by comorbidity in psychiatric research: The case of autism.Valentina Petrolini & Agustín Vicente - 2022 - Philosophical Psychology 35 (8):1234-1263.
    Despite several criticisms surrounding the DSM classification in psychiatry, a significant bulk of research on mental conditions still operates according to two core assumptions: a) homogeneity, that is the idea that mental conditions are sufficiently homogeneous to justify generalization; b) additive comorbidity, that is the idea that the coexistence of multiple conditions in the same individual can be interpreted as additive. In this paper we take autism research as a case study to show that, despite a plethora of criticism, psychiatric (...)
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  • The study of subjective experience as a scientific task for psychopathology. A commentary on Stoyanov, D., Machamer, P.K. & Schaffner, K.F. (2012). [REVIEW]Massimiliano Aragona - 2012 - Journal of Evaluation in Clinical Practice 18 (1):155-156.
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  • Epistemological reflections about the crisis of the DSM-5 and the revolutionary potential of the RDoC project.Massimiliano Aragona - 2014 - Dialogues in Philosophy, Mental and Neuro Sciences 7 (1):11-20.
    This paper tests the predictions of an epistemological model that considered the DSM psychiatric classification (in the neopositivist and neo-Kraepelinian shape introduced by the DSM-III) as a scientific paradigm in crisis. As predicted, the DSM-5 did not include revolutionary proposals in its basic structure. In particular, the possibility of a dimensional revolution has not occurred and early proposals of etiopathogenic diagnoses were not implemented due to lack of specific knowledge in that field. However, conceiving the DSM-5 as a bridge between (...)
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