In the mid-1980s, social scientists compared outcome measures of related drug studies, some funded by private companies and others by nonprofit organizations or government agencies. The concept of a “funding effect” was coined when it was discovered that study outcomes could be statistically correlated with funding sources, largely in drug safety and efficacy studies. Also identified in tobacco research and chemical toxicity studies, the “funding effect” is often attributed, implicitly or explicitly, to research bias. This article discusses the meaning of (...) scientific bias in research, examines the strongest evidence for the “funding effect,” and explores the question of whether the “funding effect” is an indicator of biased research that is driven by the financial interests of the for-profit sponsor. This article argues that the “funding effect” is merely a symptom of the factors that could be responsible for outcome disparities in product assessment. Social scientists should not suspend their skepticism and choose as a default hypothesis that bias is always or typically the cause. (shrink)

In an Isis 2008 review of research in History and Philosophy of Science (HPS), Galison opened discussion on ten on-going HPS problems. It is however unclear to what extent these problems, and constraints on their solutions, are of HPS’s own making. Recent research provides a basic resolution of these issues. In a recent paper Hooker (Perspect Sci 26(2): 266–291, 2018b) proposed that the discipline(s) of HPS should themselves also be understood to employ paradigms in HPS to understand science, analogously to (...) those employed in science to understand scientific domains. The paper argued for recognising at least two paradigms, one based on logic, and analytic forms more generally, the other based on deliberative judgement making. The present paper aims to use paradigmatic responses to Galison’s problems to explore the differing natures, merits and limitations of these two paradigms. This exploration also reveals the basic inadequacy of the analytic paradigm to illuminate the conduct of science, thereby permitting many of his problems to be dissolved rather than solved. (shrink)

The ArgumentThis paper examines the interaction between economic models and policy advice through a case study of the U.K. government's Panel of Independent Forecasters. The Panel, which met for the first time in February 1993, was part of the government's response to the policy vacuum created by its departure from the European Exchange Rate Mechanism. The paper focuses on the policy recommendations made by the Panel and their foundation in economic models. It is argued that, because of their ambiguity, economic (...) models do not provide an “objective” basis for policy making. Rather, they provide a level epistemological basis for debating the various social, political, and moral theories that can be used to frame economic policy. The paper concludes that although economic models often serve to depoliticize economic issues, they also have the potential to do exactly the opposite — namely, repoliticize them by connecting economics to wider social and moral debates. (shrink)

Deep ecology's biocentric philosophy rejects the anthropocentrism of mainstream environmentalism. Biocentrism holds that all life has inherent value and, as such, is worthy of respect and protection. Deep ecology's action strategy emerges from disgust with the compromises made by mainstream environmentalism. Deep ecologists tend toward confrontational actions such as blockades, “tree sits,” and “ecotage” (“monkey wrenching” or covert direct action). Earth First! in the United States, and Rainforest Action Network at the international level, are two well-known deep ecology groups. Bound (...) together in a complex relationship, deep ecology is both dependent on and antagonistic toward the life sciences. As yet, there is no explicit, deep ecological statement for scientific reform. But there have been scientific developments cheering to deep ecologists, including the development and growth of the new field of conservation biology. This article begins to outline the reforms necessary to bring establishment science closer to radical ecological principles. (shrink)