This paper points out the need for an analytical and ontological reorientation of the field of computer-supported cooperative work (CSCW). It is argued that even though this field is heterogeneous it is marred by general problems of conceptualising the co-constitutive relations between humans and technologies. This is demonstrated through readings of several recent CSCW analyses. It is then suggested that a conceptual improvement can be facilitated by paying attention to newer scientific studies, here exemplified by Pickering, Haraway and Latour.