In response to emergencies, it is critical to investigate how to deliver emergency supplies efficiently and securely to disaster-affected areas and people. There is no doubt that blood is deemed one of the vital relief supplies, and ensuring smooth blood delivery may substantially alleviate subsequent impacts caused by the disaster. Taking red blood cell products as the research object, this work proposes a four-echelon blood supply chain model. Specifically, it includes blood donors, blood donation houses, blood centres, and hospitals. Furthermore, (...) numerical analysis is provided to test the feasibility of blood collection and distribution schemes and conduct sensitivity analysis to test the impacts of the relevant parameters, distance between blood donors and blood facilities, and times of blood donation) on the scheme. This research provides some scientific and reasonable support for decision makers and managerial implications for emergency departments and contributes to the study of emergent blood supply chain. (shrink)