In this paper, I analyze the disruptive impact of Darwinian selectionism for the century-long tradition in which the environment had a direct causative role in shaping an organism’s traits. In the case of humans, the surrounding environment often determined not only the physical, but also the mental and moral features of individuals and whole populations. With its apparatus of indirect effects, random variations, and a much less harmonious view of nature and adaptation, Darwinian selectionism severed the deep imbrication of organism (...) and milieu posited by these traditional environmentalist models. This move had radical implications well beyond strictly biological debates. In my essay, I discuss the problematization of the moral idiom of environmentalism by William James and August Weismann who adopted a selectionist view of the development of mental faculties. These debates show the complex moral discourse associated with the environmentalist-selectionist dilemma. They also well illustrate how the moral reverberations of selectionism went well beyond the stereotyped associations with biological fatalism or passivity of the organism. Rereading them today may be helpful as a genealogical guide to the complex ethical quandaries unfolding in the current postgenomic scenario in which a revival of new environmentalist themes is taking place. (shrink)

This article focuses on Auguste Comte’s understanding of the organism–environment relationship. It makes three key claims therein: Comte’s metaphysical position privileged materiality and relativized the intellect along two dimensions: one related to the biological organism, one related to the social environment; this twofold materiality confounds attempts to reduce cognition to either nature or nurture, so Comte’s position has interesting parallels to the field of ‘epigenetics’, which sees the social environment as a causative factor in biology; and although Comte ultimately diverged (...) from the ‘postgenomic’ view in crucial ways, he remains a forerunner of the trend towards viewing the social and biological as entangled. Tending to these dimensions challenges the view that Comte is notable from a classical standpoint but ignorable from a contemporary one. It consequently invites renewed attention to his theoretical system. (shrink)

British biologist and science populariser J. B. S. Haldane was known as a contrarian, whose myriad ideas and beliefs would shift to oppose whomever he chose to argue with. Yet Haldane's support for synthetic food remained remarkably stable throughout his life. This article argues that Haldane's engagement with synthetic food during the 1930s and 1940s was shaped by his frustration with the status and direction of scientific research in Britain. Drawing upon the Haldane Papers, I reconstruct how Haldane's interest in (...) synthetic food emerged from the biochemical and physiological optimism of the early 20th century. His mid-20th-century writings were an opportunity for Haldane to voice his political opinions. He attempted to erase the conceptual divide between farm and factory, maintained that food shortages were a capitalist construct, and criticised British colonialism. By pointing out the failure of existing economic systems and governments to develop synthetic food, Haldane made the case that food production should be placed under the control of biologists. (shrink)

This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revitalized older issues, such as the relationship of life to matter, or of physicochemical inquiries to (...) biology. This scholarship points to a novel molecular vista that opens up a pluralist view of molecularizations in the twentieth century and considers their relevance to current science. (shrink)