In this paper we consider two major issues: conceptual–experimental approaches to the self, and the neuroanatomical substrate of the self. We distinguish content- and processed-based concepts of the self that entail different experimental strategies, and anatomically, we investigate the concept of midline structures in further detail and present a novel view on the anatomy of an integrated subcortical–cortical midline system. Presenting meta-analytic evidence, we show that the anterior paralimbic, e.g. midline, regions do indeed seem to be specific for self-specific stimuli. (...) We conclude that future investigation of the self need to develop novel concepts that are more empirically plausible than those currently in use. Different concepts of self will require novel experimental designs that include, for example, the brain’s resting state activity as an independent variable. Modifications of both conceptual and anatomical dimensions will allow an empirically more plausible account of the relationship between brain and self. (shrink)

Localizing the self in the brain has been the goal of consciousness research for centuries. Recently, there has been an increase in attention to the localization of the self. Here we present data from patients suffering from a loss of self in an attempt to understand the neural correlates of consciousness. Focusing on delusional misidentification syndrome , we find that frontal regions, as well as the right hemisphere appear to play a significant role in DMS and DMS related disorders. These (...) data are placed in the context of neuroimaging findings. (shrink)

In spite of enormous recent interest in the neurobiology of the self, we currently have no global models of the brain that explain how its anatomical structure, connectivity, and physiological functioning create a unified self. In this article I present a triadic neurohierarchical model of the self that proposes that the self can be understood as the product of three hierarchical anatomical systems: The interoself system, the integrative self system, and the exterosensorimotor system. An analysis of these three systems and (...) their functional features indicates that the neural hierarchy possesses features of both non-nested and nested hierarchies that are necessary for the creation of a unified consciousness and self. These functional properties also make the central nervous system a biologically unique entity unlike anything else in nature. (shrink)

Primordial emotions are the subjective element of the instincts which are the genetically programmed behaviour patterns which contrive homeostasis. They include thirst, hunger for air, hunger for food, pain and hunger for specific minerals etc.There are two constituents of a primordial emotion—the specific sensation which when severe may be imperious, and the compelling intention for gratification by a consummatory act. They may dominate the stream of consciousness, and can have plenipotentiary power over behaviour.It is hypothesized that early in animal evolution (...) complex reflex mechanisms in the basal brain subserving homeostatic responses, in concert with elements of the reticular activating system subserving arousal, melded functionally with regions embodied in the progressive rostral development of the telencephalon. This included the emergent limbic and paralimbic areas, and the insula. This phylogenetically ancient organization subserved the origin of consciousness as the primordial emotion, which signalled that the organisms existence was immediately threatened. Neuroimaging confirms major activations in regions of the basal brain during primordial emotions in humans. The behaviour of decorticate humans and animals is discussed in relation to the possible existence of primitive awareness.Neuroimaging of the primordial emotions reveals that rapid gratification of intention by a consummatory act such as ingestion causes precipitate decline of both the initiating sensation and the intention. There is contemporaneous rapid disappearance of particular regions of brain activation which suggests they may be part of the jointly sufficient and severally necessary activations and deactivations which correlate with consciousness [Crick, F. & Koch, C. . A framework for consciousness. NatureNeuroscience,6, 119–126]. (shrink)

Enhancement technologies may someday grant us capacities far beyond what we now consider humanly possible. Nick Bostrom and Anders Sandberg suggest that we might survive the deaths of our physical bodies by living as computer emulations.­­ In 2008, they issued a report, or “roadmap,” from a conference where experts in all relevant fields collaborated to determine the path to “whole brain emulation.” Advancing this technology could also aid philosophical research. Their “roadmap” defends certain philosophical assumptions required for this technology’s success, (...) so by determining the reasons why it succeeds or fails, we can obtain empirical data for philosophical debates regarding our mind and selfhood. The scope ranges widely, so I merely survey some possibilities, namely, I argue that this technology could help us determine (1) if the mind is an emergent phenomenon, (2) if analog technology is necessary for brain emulation, and (3) if neural randomness is so wild that a complete emulation is impossible. (shrink)

Many philosophers argue that the mind-body problem is unresolvable, that there are irreconcilable differences between the physical world and the way the mind experiences it. Several others argue that the problem represents an incompleteness of the Galilean view, which conceptually divides the world into two models (physical and consciousness). Recent debates have centered around a proposal to radically alter the physical model to account for the mind-body relationship. However, critics argue that the general approach is flawed and that the specific (...) proposal results in a ‘messy’ and highly complex model with inconsistencies with well-known phenomena. This paper, first, critically examines the argument that the general approach is flawed. Then this paper argues that the proposal is much broader than necessary and that the aspects required to resolve the mind-body problem are already present in the physical model. This results in, I argue, a resolution to the mind-body problem without increased complexity for either model or the aforementioned inconsistencies. (shrink)