Switch to: References

Add citations

You must login to add citations.
  1. Currents in Contemporary Bioethics: The Case against Precipitous, Population-Wide, Whole-Genome Sequencing.Mark A. Rothstein - 2012 - Journal of Law, Medicine and Ethics 40 (3):682-689.
    From the earliest days of the Human Genome Project, the holy grail of genomics was the ability to perform whole-genome sequencing quickly, accurately, and relatively inexpensively so that the benefits of genomics would be widely available in clinical settings. Although the mythical $1,000 genome sequence seemed elusive for many years, next-generation sequencing technologies and other recent advances clearly indicate that inexpensive whole-genome sequencing is at hand.Whole-genome sequencing has demonstrable value in elucidating the genetic etiology of rare disorders, in identifying atypical (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  • Ethical Concerns in the Implementation of DNA Sequencing-Based Noninvasive Prenatal Testing for Fetal Aneuploidy Among Obstetric Professionals in Hong Kong.Huso Yi, Olivia Miu Yung Ngan, Sian Griffiths & Daljit Sahota - 2015 - AJOB Empirical Bioethics 6 (1):81-93.
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  • Non‐Invasive Testing, Non‐Invasive Counseling.Rachel Rebouché - 2015 - Journal of Law, Medicine and Ethics 43 (2):228-240.
    This article describes a new prenatal genetic test that is painless, early, and increasingly available. State legislatures have reacted by prohibiting abortion for reason of fetal sex or of fetal diagnosis and managing genetic counseling. This article explores these legislative responses and considers how physicians and genetic counselors currently communicate post-testing options. The article then examines the challenges ahead for genetic counseling, particularly in light of the troubling grip of abortion politics on conversations about prenatal diagnosis.
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  • Old Questions, New Paradigms: Ethical, Legal, and Social Complications of Noninvasive Prenatal Testing.Marsha Michie & Megan Allyse - 2015 - AJOB Empirical Bioethics 6 (1):1-4.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark  
  • Prenatal Whole Genome Sequencing: An Argument for Professional Self-Regulation.Benjamin E. Berkman & Michelle Bayefsky - 2017 - American Journal of Bioethics 17 (1):26-28.
  • Expanded Non-invasive Prenatal Testing (NIPT).Zoë Claesen, Neeltje Crombag, Lidewij Henneman, Joris Robert Vermeesch & Pascal Borry - 2023 - Journal of Bioethical Inquiry 20 (1):41-49.
    Expanded non-invasive prenatal testing (NIPT) has provoked ethical concerns about its justifiable scope. In this paper, we evaluate the role of the child’s right to an open future in setting the scope of NIPT. This ‘open future principle’ has been cited in arguments both limiting and expanding parental freedoms. This moral right holds that adult autonomy rights which children cannot yet exercise should nonetheless be protected until they can. Its purpose is to protect the future autonomy of the child as (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  • A Framework for Unrestricted Prenatal Whole-Genome Sequencing: Respecting and Enhancing the Autonomy of Prospective Parents.Stephanie C. Chen & David T. Wasserman - 2017 - American Journal of Bioethics 17 (1):3-18.
    Noninvasive, prenatal whole genome sequencing may be a technological reality in the near future, making available a vast array of genetic information early in pregnancy at no risk to the fetus or mother. Many worry that the timing, safety, and ease of the test will lead to informational overload and reproductive consumerism. The prevailing response among commentators has been to restrict conditions eligible for testing based on medical severity, which imposes disputed value judgments and devalues those living with eligible conditions. (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   28 citations  
  • Implementing Expanded Prenatal Genetic Testing: Should Parents Have Access to Any and All Fetal Genetic Information?Michelle J. Bayefsky & Benjamin E. Berkman - 2022 - American Journal of Bioethics 22 (2):4-22.
    Prenatal genetic testing is becoming available for an increasingly broad set of diseases, and it is only a matter of time before parents can choose to test for hundreds, if not thousands, of genetic conditions in their fetuses. Should access to certain kinds of fetal genetic information be limited, and if so, on what basis? We evaluate a range of considerations including reproductive autonomy, parental rights, disability rights, and the rights and interests of the fetus as a potential future child. (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   16 citations  
  • What Really Matters Now in Prenatal Genetics.Megan A. Allyse & Marsha Michie - 2022 - American Journal of Bioethics 22 (2):31-33.
    We were interested to read the current target article, given our admiration for the senior author’s comprehensive coverage of these same topics a decade ago (Donley, Hul...
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  • Non-invasive Prenatal Testing for Fetal Whole Genome Sequencing: An Interpretive Critical Review of the Ethical, Legal, Social, and Policy Implications.Hazar Haidar & Renata Iskander - 2022 - Canadian Journal of Bioethics / Revue canadienne de bioéthique 5 (1).
    Introduction: Non-invasive prenatal testing allows for genetic testing of a fetus through the analysis of cell-free DNA from the mother’s plasma. NIPT is easy and safe for the fetus, since it only requires a blood draw from the mother and therefore holds no risk of miscarriage. It is considered superior to other prenatal screening tests and can also be performed earlier in the pregnancy. NIPT has the future potential for fetal whole genome sequencing for an expanded range of conditions, such (...)
    No categories
    Direct download  
     
    Export citation  
     
    Bookmark