The answer to some of the longstanding issues in the 20th century theoretical physics, such as those of the incompatibility between general relativity and quantum mechanics, the broken symmetries of the electroweak force acting at the subatomic scale and the missing mass of Higgs particle, and also those of the cosmic singularity and the black matter and energy, appear to be closely related to the problem of the quantum texture of space-time and the fluctuations of its underlying geometry. Each region (...) of space landscape seem to be filled with spacetime weaved and knotted networks, for example, spacetime has immaterial curvature and structures, such as topological singularities, and obeys the laws of quantum physics. Thus, it is filled with potentialparticles, pairs of virtual matter and anti-matter units, and potential properties at the quantum scale. For example, quantum entities (like fields and particles) have both wave (i.e., continuous) and particle (i.e., discrete) properties and behaviors. At the quantum level (precisely, the Planck scale) of space-time such properties and behaviors could emerge from some underlying (dynamic) phase space related to some field theory. Accordingly, these properties and behaviors leave their signature on objects and phenomena in the real Universe. In this paper we consider some conceptual issues of this question. (shrink)