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  1. Non-epistemic values in shaping the parameters for evaluating the effectiveness of candidate vaccines: the case of an Ebola vaccine trial.Joby Varghese - 2021 - History and Philosophy of the Life Sciences 43 (2):1-15.
    This paper examines the case of Ebola, ça Suffit trial which was conducted in Guinea during Ebola Virus Disease (EVD) outbreak in 2015. I demonstrate that various non-epistemic considerations may legitimately influence the criteria for evaluating the efficacy and effectiveness of a candidate vaccine. Such non-epistemic considerations, which are social, ethical, and pragmatic, can be better placed and addressed in scientific research by appealing to non-epistemic values. I consider two significant features any newly developed vaccine should possess; (1) the duration (...)
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  • Sharpening the cutting edge: additional considerations for the UK debates on embryonic interventions for mitochondrial diseases.Erica Haimes & Ken Taylor - 2017 - Life Sciences, Society and Policy 13 (1):1-25.
    In October 2015 the UK enacted legislation to permit the clinical use of two cutting edge germline-altering, IVF-based embryonic techniques: pronuclear transfer and maternal spindle transfer. The aim is to use these techniques to prevent the maternal transmission of serious mitochondrial diseases. Major claims have been made about the quality of the debates that preceded this legislation and the significance of those debates for UK decision-making on other biotechnologies, as well as for other countries considering similar legislation. In this article (...)
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  • Ebola: what it teaches us about medical ethics. A response to Angus Dawson.Bridget G. Haire & Morenike O. Folayan - 2016 - Journal of Medical Ethics 42 (1):59-60.
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  • Aspects of disaster research ethics applicable to other contexts.Bridget Haire - 2018 - Journal of Medical Ethics 44 (1):9-10.
    In his article ‘The Ebola Clinical Trials: a precedent for research ethics in disasters’, Philippe Calain constructs a compelling case as to why and how experiences from the recent Ebola epidemic should be used to develop a framework for disaster research ethics. In particular, Calain proposes a useful model for assessing whether or not an unproven intervention could be suitable for human use in a disaster context, and makes a powerful argument against the separation of patient care from research goals. (...)
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  • Defending the four principles approach as a good basis for good medical practice and therefore for good medical ethics.Raanan Gillon - 2015 - Journal of Medical Ethics 41 (1):111-116.
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  • Public Health: Beyond the Role of the State.Angus Dawson & Marcel Verweij - 2015 - Public Health Ethics 8 (1):1-3.
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  • Pandemic vaccine trials: expedite, but don’t rush.Angus Dawson - 2020 - Research Ethics 16 (3-4):1-12.
    It has been proposed that the urgency of having a vaccine as a response to SARS-CoV-2 is so great, given the potential health, economic and social benefits that we should override the established s...
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  • One Health, Vaccines and Ebola: The Opportunities for Shared Benefits.Benjamin Capps & Zohar Lederman - 2015 - Journal of Agricultural and Environmental Ethics 28 (6):1011-1032.
    The 2013 Ebola virus outbreak in West Africa, as of writing, is declining in reported human cases and mortalities. The resulting devastation caused highlights how health systems, in particular in West Africa, and in terms of global pandemic planning, are ill prepared to react to zoonotic pathogens. In this paper we propose One Health as a strategy to prevent zoonotic outbreaks as a shared goal: that human and Great Ape vaccine trials could benefit both species. Only recently have two phase (...)
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  • The Ebola clinical trials: a precedent for research ethics in disasters.Philippe Calain - 2018 - Journal of Medical Ethics 44 (1):3-8.
    The West African Ebola epidemic has set in motion a collective endeavour to conduct accelerated clinical trials, testing unproven but potentially lifesaving interventions in the course of a major public health crisis. This unprecedented effort was supported by the recommendations of an ad hoc ethics panel convened in August 2014 by the WHO. By considering why and on what conditions the exceptional circumstances of the Ebola epidemic justified the use of unproven interventions, the panel's recommendations have challenged conventional thinking about (...)
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  • The Ebola clinical trials: a precedent for research ethics in disasters.Philippe Calain - 2017 - Journal of Medical Ethics Recent Issues 44 (1):3-8.
    The West African Ebola epidemic has set in motion a collective endeavour to conduct accelerated clinical trials, testing unproven but potentially lifesaving interventions in the course of a major public health crisis. This unprecedented effort was supported by the recommendations of an ad hoc ethics panel convened in August 2014 by the WHO. By considering why and on what conditions the exceptional circumstances of the Ebola epidemic justified the use of unproven interventions, the panel's recommendations have challenged conventional thinking about (...)
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  • Ethical Challenges of the Zika Epidemic.Ann Boyd, Marie Winpigler & Enrique Figueroa - 2018 - Eubios Journal of Asian and International Bioethics 28 (5):154-157.
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