The coevolution of objectivity and subjectivity and the nature of both their division and connection are central to this paper. Section 2 addresses the nature of meaning from the subjective perspective. Initially, I examine the meaningful engagement that exists between the unicellular organism and its environment. In this respect, I focus on the ontological importance of the qualitative biochemical assimilation of the physical rather than on the evolution of form and function. In Section 3, I broaden the discussion to include (...) multicellular organisms and introduce the idea that meaning, at various levels, qualifies different objective and informational constructs of the world. These determine the character of interactive engagement and reveal much about the way in which an agent signifies the external. In Section 4, I review Darwinian evolution from the position of the existential self. I emphasize that meaning is that which qualifies the human concept of objectivity, rather than that objectivity is that which will help humankind qualify or understand meaning. Ultimately, this outlook challenges scientific disciplines that have tended to obscure the relevance of meaning and sought, instead, to explain it from an epistemological footing. In its overall scope, I try to establish the view that the subjective and objective domains are more nuanced, layered, and intertwined ontologically than the default stance that presents a binary juxtaposition between the two. (shrink)