my introduction to special issue of Science in Context on 18c vitalism.

The ArgumentMicroscopical consideration played a crucial role in German physiology in the period of, grosso modo, 1780–1830. Specifically, a conception of material change was established, according to which all life is grounded in the process of the generation of microscopical forms out of an amorphous, primitive generative substance. Embryological development, tissue growth, and the generation of microorganisms were all considered to be the manifestation of this fundamental developmental process. In contrast to the common historiography, I try to understand Theodor Schwann's (...) 1838 discovery of the cell theory in terms of the epistemological categories he applied to the prevailing conceptions of life and living matter. I argue that Schwann was able to discern cells not because of any superior microscopical methods, but rather as part of his wider investigative endeavor to explicate life processes according to specific causal agents. I argue that Schwann was able to demonstrate the existence of cells only when he considered animal tissues in terms of a causal relation between specific material agents and their effect, that is, the developmental history of tissue. (shrink)

While historians of the microscope currently consider that no programme of microscopy took place during the Enlightenment, the thesis challenges this view and aims at showing when and where microscopes were used as research tools. The focus of the inquiry is the research on microscopic animalcules and the relationship of European microscope making and practices of microscopy with topical trends of the industrial revolution, such as quantification. Three waves of research are characterised for the research on animalcules in the Enlightenment: (...) 1. seventeenth-century observations on animalcules crowned by Louis Joblot's 1718 works in the milieu of Paris Académie royale des sciences, 2. mid eighteenth-century observations and experiments on polyps and animalcules (Trembley, Baker and Hill) and, 3. between 1760 and 1790, OF Müller's establishment of the systematics of infusoria in Denmark and Germany. (shrink)