As a significant extension of our previous calculus of logical differentials and moving logic, we propose here a mathematical diagram for specifying the emergence of novelty, through the construction of some “differentials” related to cohomological computations. Later we intend to examine how to use these “differentials” in the analysis of anticipation or evolution schemes. This proposal is given as a consequence of our comments on the Ehresmann–Vanbremeersch’s work on memory evolutive systems, from the two points of view which are characterization (...) of life and use of categorical modeling. It would not be possible to conceive of the “differentials” outside the frame of a MES. Furthermore, we hope that this diagram will be useful to exhibit the “emergence of sense” in discourses, and this idea is supported here by a brief examination of how a discourse could be seen as a living system. (shrink)