Given a huge variety of international relations in the age of globalization, business ethics needs to take them seriously in a differentiated way with great sensitivity and sophisticated understanding. This essay proposes to structure the field of business ethics by distinguishing three levels of analysis and four types of international relations. It builds on Richard T. De George’s pioneering work as an early leader in the field of business ethics. It is hoped that such differentiation may help to better identify (...) the ethical responsibilities of all actors in business and the economy. The first part explains the extended three-level conception of business ethics with four types of international relations. The second part shows De George’s contribution to substantiate this conceptual framework. And the third part discusses the significance of this framework for better ways of securing human rights in international relations. (shrink)