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  1. Are ‘phase IV’ trials exploratory or confirmatory experiments?Austin Due - 2022 - Studies in History and Philosophy of Science Part A 95 (C):126-133.
    Exploratory experiments are widely characterized as experiments that do not test hypotheses. Experiments that do test hypotheses are characterized as confirmatory experiments. Philosophers have pointed out that research programmes can be both confirmatory and exploratory. However, these definitions preclude single experiments being characterized as both exploratory and confirmatory; how can an experiment test and not test a hypothesis? Given the intuition that some experiments are exploratory, some are confirmatory, and some are both, a recharacterization of the relationship between exploratory and (...)
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  • What do international ethics guidelines say in terms of the scope of medical research ethics?Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. van Thiel & Johannes J. M. van Delden - 2016 - BMC Medical Ethics 17 (1):1-18.
    BackgroundIn research ethics, the most basic question would always be, “which is an ethical issue, which is not?” Interestingly, depending on which ethics guideline we consult, we may have various answers to this question. Though we already have several international ethics guidelines for biomedical research involving human participants, ironically, we do not have a harmonized document which tells us what these various guidelines say and shows us the areas of consensus. In this manuscript, we attempted to do just that.MethodsWe extracted (...)
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