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  1. Rethinking Neuroscientific Methodology: Lived Experience in Behavioral Studies.Nedah Nemati - forthcoming - Biological Theory:1-14.
    The role of experience in the process of behavioral refinement has been undertheorized by philosophers of neuroscience and neuroscientists. By examining sleep studies in behavioral neurobiology, I show that scientists frequently invoke a variety of lived experiences—what I call experientially derived notions—to refine the behavior under investigation. Of note, these behaviors must remain sufficiently fuzzy throughout experimentation to permit refinement. The aim of this article is to recognize that neuroscientists’ use of lived experience necessarily helps refine behaviors and render those (...)
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  • La deriva genética como fuerza evolutiva.Ariel Jonathan Roffé - 2015 - In J. Ahumada, N. Venturelli & S. Seno Chibeni (eds.), Selección de Trabajos del IX Encuentro AFHIC y las XXV Jornadas de Epistemología e Historia de la ciencia. pp. 615-626.
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  • From depressed mice to depressed patients: a less “standardized” approach to improving translation.Monika Piotrowska - 2023 - Biology and Philosophy 38 (6):1-19.
    Depression is a widespread and debilitating disorder, but developing effective treatments has proven challenging. Despite success in animal models, many treatments fail in human trials. While various factors contribute to this translational failure, standardization practices in animal research are often overlooked. This paper argues that certain standardization choices in behavioral neuroscience research on depression can limit the generalizability of results from rodents to humans. This raises ethical and scientific concerns, including animal waste and a lack of progress in treating human (...)
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  • From Microscopes to Optogenetics: Ian Hacking Vindicated.John Bickle - 2018 - Philosophy of Science 85 (5):1065-1077.
    I introduce two new tools in experimental neurobiology, optogenetics and DREADDs. These tools permit unprecedented control over activity in specific neurons in behaving animals. In addition to their inherent scientific interest, these tools make an important contribution to philosophy of science. They illustrate the very premises of Ian Hacking’s “microscope” argument for the relative independence of experiment from theory. This new example is important for generalizing Hacking’s argument because the background sciences and the fields of engineering producing these tools differ (...)
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  • It’s a Male World : el sesgo sexual de los modelos animales en biología.Federico Bernabé Blach & Leandro Giri - 2019 - Arbor 195 (791):492.
    En el presente trabajo se analizan desde un punto de vista metateórico los modelos animales y su uso en la investigación en el ámbito de las ciencias de la vida. A partir de la evaluación de una nutrida literatura científica que denuncia un sesgo sexual en las prácticas de investigación que utilizan dichos modelos, se buscan los supuestos teóricos implícitos que les dan fundamento y se argumenta que lejos de suponer una torpeza metodológica forman parte de una extensa tradición ubicua (...)
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