Recent studies have shown that Hugo de Vries did not rediscover Mendel's laws independently and that the classical story of the rediscovery of Mendel is largely a myth. Until now, however, no satisfactory account has been provided of the background and development of de Vries' views on heredity and evolution. The basic tenets of de Vries' Mutationstheorie and his conception of Mendelism are still insufficiently understood. It has been suggested that de Vries failed to assimilate Mendelism and that he wrote (...) his Mutationstheorie in a state of confusion. In this paper I argue that we can arrive at a better understanding by adopting a more symmetrical approach. My analysis will concentrate on three important aspects of de Vries' thinking which have been insufficiently appreciated until now. The first is that de Vries' reading of Mendel compelled him to change his conception of the hereditary particles, the pangenes, in a fundamental way. The second is de Vries' use of the notion of ‘hereditary force’. The third revolves around de Vries' typological species concept, which has been the source of much confusion in the literature. I shall conclude that de Vries did succeed in incorporating ‘Mendelism’ into his wider views on heredity and evolution, and that he did manage to handle his evidence in a consistent way. Yet I shall also conclude that Mendelism, in de Vries' interpretation, had nothing to do with ‘normal’ heredity and was mainly a laboratory phenomenon. (shrink)

The analogy between artificial selection of domestic varieties and natural selection in nature was a vital element of Darwin's argument in his Origin of Species. Ever since, the image of breeders creating new varieties by artificial selection has served as a convincing illustration of how the theory works. In this paper I argue that we need to reconsider our understanding of Darwin's analogy. Contrary to what is often assumed, nineteenth-century animal breeding practices constituted a highly controversial field that was fraught (...) with difficulties. It was only with considerable effort that Darwin forged his analogy, and he only succeeded by downplaying the importance of two other breeding techniques - crossing of varieties and inbreeding - that many breeders deemed essential to obtain new varieties. Part of the explanation for Darwin's gloss on breeding practices, I shall argue, was that the methods of his main informants, the breeders of fancy pigeons, were not representative of what went on in the breeding world at large. Darwin seems to have been eager to take the pigeon fanciers at their word, however, as it was only their methods that provided him with the perfect analogy with natural selection. Thus while his studies of domestic varieties were important for the development of the concept of natural selection, the reverse was also true: Darwin's comprehension of breeding practices was moulded by his understanding of the working of natural selection in nature. Historical studies of domestic breeding practices in the eighteenth and nineteenth century confirm that, besides selection, the techniques of inbreeding and crossing were much more important than Darwin's interpretation allowed for. And they still are today. This calls for a reconsideration of the pedagogic use of Darwin's analogy too. (shrink)

In the 1940s and 1950s, Dutch scientists became increasingly critical of the practices of commercial dairy cattle breeders. Milk yields had hardly increased for decades, and the scientists believed this to be due to the fact that breeders still judged the hereditary potential of their animals on the basis of outward characteristics. An objective verdict on the qualities of breeding stock could only be obtained by progeny testing, the scientists contended: the best animals were those that produced the most productive (...) offspring. Some scientists had been making this claim since the beginning of the twentieth century. Why was it that their advice was apparently not heeded by breeders for so long? And what were the methods and beliefs that guided their practices? In this paper I intend to answer these questions by analysing the practical realities of dairy farming and stock breeding in The Netherlands between 1900 and 1950. Breeders continued to employ traditional breeding methods that had proven their effectiveness since the late eighteenth century. Their methods consisted in inbreeding - breeding in 'bloodlines,' as they called it - and selection on the basis of pedigree, conformation and milk recording data. Their aims were 'purity' and 'uniformity' of type. Progeny testing was not practiced due to practical difficulties. Before World War II, scientists acknowledged that genetic theory was of little practical use to breeders of livestock. Still, hereditary theory was considered to be helpful to assess the value of the breeders' methods. For instance, striving for purity was deemed to be consistent with Mendelian theory. Yet the term purity had different connotations for scientists and practical workers. For the former, it referred to homozygosity; for the latter, it rather buttressed the constancy of a distinct commercial ' brand.' Until the 1940s, practical breeders and most scientists were agreed that selecting animals purely for production was ill-advised. Cows of the extreme dairy type were believed to be prone to bovine tuberculosis. This conviction was at the basis of the development of 'the modern Friesian,' a rather robust type of dairy cow that was also valued for its aesthetically pleasing conformation and that became a commercial success. Contrary to the scientists' claims, it was not only for commercial reasons that breeders were reluctant to give up their modern Friesians after World War II, when the introduction of artificial insemination opened up the possibility of breeding more productive types by means of progeny testing. The political economy of breeding did indeed require breeders to protect their breed as a recognisable brand. Yet the moral economy of breeding must also be taken into account: the modern Friesian was also a product of widely shared normative standards of good and responsible farming. (shrink)

Historians of science have repeatedly, and justly, pointed to the discrepancy between theory and practice in the writings of Cuvier. This discrepancy is especially conspicious in his palaeontological works. No satisfactory analysis of the relation between theory and practice in Cuvier's palaeontology has appeared as yet. In this paper I shall point out the shortcomings of the interpretations of E. S. Russell, H. Daudin, W. Coleman, M. J. S. Rudwick and B. Balan. These authors either overrated or underestimated the role (...) Cuvier's anatomical rules played in his research. Next I shall argue that theory, as embodied in the anatomical rules, played an important role in Cuvier's study of fossil animals. However, the rules were not used as abstract principles of reconstruction. It is a persistent misconception that Cuvier's main concern in the Recherches sur les ossemens fossiles was the reconstruction of extinct animals. Most memoirs deal only with the identification, description and classification of fossil remains. It was mainly on this level that Cuvier—successfully—applied the anatomical rules. As an example of the use he made of the rules, Cuvier's study of the fossil mosasaur from Masstricht will be discussed. This example will also provide a clue to an alternative explanation of the discrepancy between theory and practice in the Recherches. I shall argue that Cuvier's theoretical claims must in part be qualified as examples of his great talent for image-building. (shrink)

In the 1940s and 1950s, Dutch scientists became increasingly critical of the practices of commercial dairy cattle breeders. Milk yields had hardly increased for decades, and the scientists believed this to be due to the fact that breeders still judged the hereditary potential of their animals on the basis of outward characteristics. An objective verdict on the qualities of breeding stock could only be obtained by progeny testing, the scientists contended: the best animals were those that produced the most productive (...) offspring. Some scientists had been making this claim since the beginning of the twentieth century. Why was it that their advice was apparently not heeded by breeders for so long? And what were the methods and beliefs that guided their practices? In this paper I intend to answer these questions by analysing the practical realities of dairy farming and stock breeding in The Netherlands between 1900 and 1950. Breeders continued to employ traditional breeding methods that had proven their effectiveness since the late eighteenth century. Their methods consisted in inbreeding - breeding in 'bloodlines,' as they called it - and selection on the basis of pedigree, conformation and milk recording data. Their aims were 'purity' and 'uniformity' of type. Progeny testing was not practiced due to practical difficulties. Before World War II, scientists acknowledged that genetic theory was of little practical use to breeders of livestock. Still, hereditary theory was considered to be helpful to assess the value of the breeders' methods. For instance, striving for purity was deemed to be consistent with Mendelian theory. Yet the term purity had different connotations for scientists and practical workers. For the former, it referred to homozygosity; for the latter, it rather buttressed the constancy of a distinct commercial ' brand.' Until the 1940s, practical breeders and most scientists were agreed that selecting animals purely for production was ill-advised. Cows of the extreme dairy type were believed to be prone to bovine tuberculosis. This conviction was at the basis of the development of 'the modern Friesian,' a rather robust type of dairy cow that was also valued for its aesthetically pleasing conformation and that became a commercial success. Contrary to the scientists' claims, it was not only for commercial reasons that breeders were reluctant to give up their modern Friesians after World War II, when the introduction of artificial insemination opened up the possibility of breeding more productive types by means of progeny testing. The political economy of breeding did indeed require breeders to protect their breed as a recognisable brand. Yet the moral economy of breeding must also be taken into account: the modern Friesian was also a product of widely shared normative standards of good and responsible farming. (shrink)

Keine ausführliche Beschreibung für "Der Andere" verfügbar.

Frontmatter -- Vorwort -- Inhalt -- 1 Antike Melancholie -- 2 Die Acedia des Mittelalters -- 3 Moderne Metamorphosen -- Anmerkungen.

Niemand dacht oorspronkelijker, speelser en scherper dan Ludwig Wittgenstein, en hij wist het. Van de kristallijnen helderheid in de 'Tractatus' tot de alledaagse onoverzichtelijkheid van de 'Filosofische onderzoekingen' blijft zijn denken één lange worsteling tegen de betovering van ons intellect door de schier eindeloze variatie van vermommingen waarin taal de gedachte aan het oog onttrekt.0Wittgenstein wist dat hij een bijzonder talent had, en zijn visie op zichzelf is zeker zo boeiend als zijn kijk op de wereld. In zijn brieven en (...) dagboeken treedt een geniale, lastige, komische en ontroerende man naar voren die in leven en in sterven een onuitwisbare indruk maakte op de mensen die hem kenden.0Bert Keizer biedt een heldere en toegankelijke introductie in leven en werk van Wittgenstein. Hij bespreekt diens brieven, dagboeken en belangrijkste werken: de 'Tractatus', de 'Filosofische onderzoekingen' en 'Over zekerheid'. Dat doet hij gedreven en enthousiast, zonder belerend te worden.0. (shrink)

Keine ausführliche Beschreibung für "Der Andere" verfügbar.

Hoewel depressie veel voorkomt, tasten we wat betreft de aard en behandeling ervan nog altijd in het duister. Dit komt volgens Van den Bergh omdat de stoornis vooral wordt benaderd als hersenziekte of hersenaandoening. De nadruk wordt daarbij gelegd op onze (neuro)biologische gevoeligheid zonder dat we echt stilstaan bij de maatschappelijke factoren die op deze gevoeligheid inwerken. Nog minder, aldus de auteur, wordt ingegaan op de culturele bronnen van deze impact. Deze blinde vlek in de depressieduiding stelt Van den Bergh (...) in zijn boek centraal, en werpt zo een tegenlicht op het gangbare begrip van deze ‘stemmingsstoornis’. (shrink)

Unter welchen Bedingungen kann es als ethisch vertretbar gelten, Menschen in biomedizinischen Experimenten als Probanden einzusetzen? Bert Heinrichs unternimmt es, die Ethik der Forschung am Menschen grundlegend und systematisch zu erschließen. Seine ethische Rahmentheorie wird im Hinblick auf drei kontrovers diskutierte Problemkomplexe ausgewertet, nämlich die Forschung mit Minderjährigen, randomisierte klinische Studien und Forschung in Entwicklungsländern. Sie soll helfen, wesentliche Orientierung bei der konkreten Problemlösung zu geben.

In spite of the remarkable progress made in the burgeoning field of social neuroscience, the neural mechanisms that underlie social encounters are only beginning to be studied and could —paradoxically— be seen as representing the ‘dark matter’ of social neuroscience. Recent conceptual and empirical developments consistently indicate the need for investigations, which allow the study of real-time social encounters in a truly interactive manner. This suggestion is based on the premise that social cognition is fundamentally different when we are in (...) interaction with others rather than merely observing them. In this article, we outline the theoretical conception of a second-person approach to other minds and review evidence from neuroimaging, psychophysiological studies and related fields to argue for the development of a second-person neuroscience, which will help neuroscience to really go social; this may also be relevant for our understanding of psychiatric disorders construed as disorders of social cognition. (shrink)

Doing Right: A Practical Guide to Ethics for Medical Trainees and Physicians is a concise and practical guide to ethical decision-making in medicine. The text is aimed at second- and third-year one-semester ethics courses offered in medical schools, health sciences departments, and nursing programs. By taking an applied approach rather than a theoretical approach, this text serves the needs of medical and nursing students, residents, and practicing physicians by sorting through questions of moral principles relevant to the diverse and growing (...) number of healthcare professionals. The many topics covered include truth telling, refusal of treatment, assisted suicide, managing error, and reproductive choice. (shrink)

Foucault nous a donne de multiples potentialites pour repenser certaines des questions classiques posees par l histoire et les sciences des religions. Cet ouvrage fait etat des nombreux excursus du philosophe vers les domaines de la spiritualite antique, de l histoire du christianisme primitif, de l ascetisme chretien, ou encore de la question des marginalites religieuses. Il est l occasion, surtout, de reflechir sur quelques uns des - outils - mis en place par le philosophe et de montrer comment ceux-ci (...) peuvent se reveler pertinents pour saisir les phenomenes religieux de notre modernite. Des phenomenes qui se comprennent a l interieur de problemes historiques, politiques et sociaux, culturels. Seule maniere, repete Foucault, de nous proteger contre les syntheses toutes faites et les decoupages familiers, mais aussi d ouvrir la reflexion a l epreuve de la realite et de l actualite. Jean-Francois Bert est Maitre d enseignement et de recherche a l Universite de Lausanne. Specialiste de l histoire des sciences humaines, il developpe une nouvelle approche qui se veut attentive aux pratiques et aux techniques savantes. Il a codirige le Cahier de l Herne sur Foucault (2011), et a participe a l edition, en Pleiade, des oeuvres du philosophe.". (shrink)

Drawing on his extensive experience as both a medical practitioner and a patient, acclaimed author, award-winning physician, and ethicist Philip Hébert creates a brave and intimate portrait of the complex ethical questions raised by revolutionary advances in medical diagnosis and treatment. Philip Hébert addresses the complex ethical questions raised by revolutionary advances in medical treatment. This work expands upon Hébert's previous book, "Doing Right," and extends his knowledge of the field beyond medical professionals to reach the patients they treat.

In this article, I present two conceptual problems for Craver's mutual manipulability account of constitutive relevance in mechanisms. First, constitutive relevance threatens to imply causal relevance despite Craver (and Bechtel)'s claim that they are strictly distinct. Second, if (as is intuitively appealing) parthood is defined in terms of spatio-temporal inclusion, then the mutual manipulability account is prone to counterexamples, as I show by a case of endosymbiosis. I also present a methodological problem (a case of experimental underdetermination) and formulate two (...) partial, but fallible solutions based on the notions of parthood and synchronicity. (shrink)

Purpose The purpose of this paper is to develop an ethical framework for the marketing of corporate social responsibility. Methods The approach is a conceptual one based on virtue ethics and on the corporate identity literature. Furthermore, empirical research results are used to describe the opportunities and pitfalls of using marketing communication tools in the strategy of building a virtuous corporate brand. Results/conclusions An ethical framework that addresses the paradoxical relation between the consequentialist perspective many proponents of the marketing of (...) CSR adopt, and ethical perspectives which criticize an exclusive profit-oriented approach to CSR. Furthermore, three CSR strategies in relation to the marketing of CSR are discussed. For each CSR strategy it is explored how a corporation could avoid falling into the promise/performance gap. (shrink)

Today, mechanisms and mechanistic explanation are very popular in philosophy of science and are deemed a welcome alternative to laws of nature and deductive‐nomological explanation. Starting from Mitchell's pragmatic notion of laws, I cast doubt on their status as a genuine alternative. I argue that (1) all complex‐systems mechanisms ontologically must rely on stable regularities, while (2) the reverse need not hold. Analogously, (3) models of mechanisms must incorporate pragmatic laws, while (4) such laws themselves need not always refer to (...) underlying mechanisms. Finally, I show that Mitchell's account is more encompassing than the mechanistic account *Received August 2008; revised January 2010. †To contact the author, please write to: Centre for Logic and Philosophy of Science, Ghent University, Blandijnberg 2, B‐9000 Belgium; e‐mail: Bert[email protected]. (shrink)

Many theories about human number representation stress the importance of a central semantic representation that includes the magnitude information of small integer numbers, and that is conceived as an abstract, compressed number line. However, thus far there has been little or no direct evidence that units and teens are represented on the same number line. In two masked priming experiments, we show that single-digit and two-digit Arabic numerals are equally well primed by an Arabic numeral with the same number of (...) digits as by an equally distant Arabic numeral with a different number of digits (e.g. the priming effect of 7 on the target 9 is the same as the priming effect of 11 on the target 9). The finding was obtained both with a number naming task and with a parity judgement task. This is in line with the hypothesis that units and teens are part of a continuous number line. (shrink)

This volume compares the western ideas of knowledge with the African. It aims at creating a mirror through which the western knowledge culture can look at itself through an unusual and interesting angle. The culture of Sub-Saharan Africa is the substance from which we, in this book, have tried to construe an epistemological mirror.

"Op 9 december 2011 was het precies zeventig jaar geleden dat de Joodse rechtsfilosoof, vrijdenker en humanist Leo Polak (1880-1941) in het concentratiekamp Sachsenhausen overleed. De essentie van zijn vrijdenken en humanisme getuigt van het besef van de verbondenheid van alle mensen als wezens die zich zo volledig en harmonieus mogelijk moeten kunnen ontplooien, en de erkenning van de mensheid als hoogste eenheid, hoger dan alle andere collectiviteiten die loyaliteit van mensen zouden kunnen eisen: kerk, Christendom, natie. Deze bundel bevat (...) als kern een drietal beroemde en beruchte redevoeringen van Polak uit de jaren 1931-1933; deze waren idealistisch van aard en vonden veel instemming bij met name ongelovigen. Daarnaast zijn er diverse bijdragen die een goed en soms nieuw beeld geven van de rol en betekenis van Polak voor de vrijdenkers; zo had hij op belangrijke momenten een koersbepalende rol in de geschiedenis van de vrijdenkerij."--Page 4 of cover. (shrink)

We analyze ethical policies of firms in industrialized countries and try to find out whether culture is a factor that plays a significant role in explaining country differences. We look into the firm’s human rights policy, its governance of bribery and corruption, and the comprehensiveness, implementation and communication of its codes of ethics. We use a dataset on ethical policies of almost 2,700 firms in 24 countries. We find that there are significant differences among ethical policies of firms headquartered in (...) different countries. When we associate these ethical policies with Hofstede’s cultural indicators, we find that individualism and uncertainty avoidance are positively associated with a firm’s ethical policies, whereas masculinity and power distance are negatively related to these policies. (shrink)

4e de couv.: Les écrits de Michel Foucault sont stratifiés, hiérarchisés, entre les livres, les entretiens et les cours au Collège de France, mais ils sont surtout disséminés dans leurs usages. Désormais, et en plus de l'histoire des sciences et de la philosophie, les "effets" Foucault sont palpables sur la théorie de la littérature et du cinéma, l'histoire culturelle et sociale, les théories du genre, la pensée politique, les sciences de gestion, etc. C'est dans ce chantier ouvert que se situe (...) cet ouvrage. Il s'agit pour Jérôme Lamy, Jean-François Bert et leur équipe de spécialistes de resituer et d'analyser une pensée empruntant des questionnements à d'autres champs, de la psychologie à l'économie, de la science politique à la géographie, tout en ne se réclamant pas de ces sciences humaines et sociales. Pour comprendre la position de Foucault, les grands axes méthodologiques qu'il a parcourus sont retracés, telle l'archéologie, l'épistémè, la problématisation. Les concepts, des ouvrages maintenant classiques aux cours et à l'histoire de la sexualité, sont également revisités. Cette lecture critique des écrits et des usages de Foucault permet de le confronter aux analyses les plus récentes en sciences sociales, comme les postcolonial studies, ou de suivre les dialogues engagés (parfois à distance) avec des auteurs comme Norbert Elias, Michel de Certeau et Pierre Bourdieu. Un inventaire aussi rigoureux qu'éclairant. (shrink)

This article offers a general discussion of the concept of false hope. Its ultimate aim is to clarify the meaning and the relevance of that concept for medicine and medical research. In the first part, the concept of hope is discussed. I argue that hope is more than a combination of a desire and a belief about the probability that the desire will be fulfilled. Imagination and anticipation are as well components of hope. I also discuss if hope implies orientation (...) to action. In the second part, I examine the concept of false hope. I show that hope is false if it cannot be justified epistemically. There is, I argue, an intimate relation between false hope and ignorance. Hope is justified—“realistic”—when the hoping person knows and accepts experts’ judgement about the probability of hope fulfillment. I then argue that what matters for evaluating a person’s hope is not only whether it is realistic, but also whether it is reasonable in the light of the aim and goals that a person strives for in his life. Part three goes into the question of what is morally wrong about having or causing false hope. In the fourth part, the relevance is shown of the insights from the previous parts for the debate on false hope in medicine and clinical research. (shrink)

Empirische Ethik ist ein relativ neues Vorgehen in der Ethikforschung, das vor allem in der Medizinethik angewandt wird. Dieser Beitrag bespricht die kennzeichnenden Charakteristika der empirischen Ethik und unterscheidet zwischen generalistischer und kontextualistischer empirischer Ethik. Zuerst werden verschiedene Beispiele beider Arten von empirischer Ethik vorgestellt, danach werden für beide Ansätze mögliche Schwachpunkte diskutiert. Die Schlussfolgerung des Beitrages besteht darin, dass das Entstehen der empirischen Ethik eine positive Entwicklung ist. Empirische Ethik sollte jedoch als eine Ergänzung der traditionellen philosophischen Medizinethik betrachtet (...) werden, und nicht als die bessere Alternative. (shrink)