While an ethical obligation to report findings of clinical research to trial participants is increasingly recognised, the academic debate is often vague about what kinds of data should be fed back and how such a process should be organised. In this article, we present a classification of different actors, processes and data involved in the feedback of research results pertaining to an individual. In a second step, we reflect on circumstances requiring further ethical consideration. In regard to a concrete research (...) setting—the one of clinico-genomic research—we discuss what kinds of difficulties have to be faced when returning individual research results to trial participants. In a last step, we elaborate on a stepwise model to trigger the individual feedback process. Hence, this paper gives guidance on how to feedback individual research results in a specific research setting and responds at the same time to new challenges in the debate on the duty to return individual research findings. (shrink)

Die prospektive Analyse der ethischen Implikationen medizinisch-technischer Innovationen läuft immer auch Gefahr, sich in den Wunschbildern von Marketingexperten zu verfangen. Vor diesem Hintergrund könnte es durchaus nützlich sein, die Erkenntnisse der Wissenschafts- und Technikforschung zur Genese und Entwicklung neuer Techniken auszuschöpfen. Dies erscheint gerade auch für die ins Phantastische weisende Zukunft der Individualisierung medikamentöser Therapie, wie man ihr häufig in der Beschreibung pharmakogenetischer Behandlungskonzepte begegnet, angebracht. Techniken, die sich noch im Entwicklungsstadium befinden und deren breite Anwendung noch einige Jahre auf (...) sich warten lassen wird, sollten sehr sorgfältig auf ihren Realitätsgehalt und das zu erwartende Leistungspotenzial hin analysiert werden. Dazu gehört v. a. auch eine kritische Auseinandersetzung mit den Leitbildern, Visionen und Nutzenversprechen, mit denen technische Innovationen oft sehr absichtsvoll ausgestattet werden. Wird dabei die Distanz zur Rhetorik der Protagonisten der neuen Techniken nicht gewahrt, gerät die ethische Reflexion unvermittelt in die Rolle, profane Marketingstrategien wortgewandt und ideenreich zu veredeln. (shrink)

ZusammenfassungDie prospektive Analyse der ethischen Implikationen medizinisch-technischer Innovationen läuft immer auch Gefahr, sich in den Wunschbildern von Marketingexperten zu verfangen. Vor diesem Hintergrund könnte es durchaus nützlich sein, die Erkenntnisse der Wissenschafts- und Technikforschung zur Genese und Entwicklung neuer Techniken auszuschöpfen. Dies erscheint gerade auch für die ins Phantastische weisende Zukunft der Individualisierung medikamentöser Therapie, wie man ihr häufig in der Beschreibung pharmakogenetischer Behandlungskonzepte begegnet, angebracht. Techniken, die sich noch im Entwicklungsstadium befinden und deren breite Anwendung noch einige Jahre auf (...) sich warten lassen wird, sollten sehr sorgfältig auf ihren Realitätsgehalt und das zu erwartende Leistungspotenzial hin analysiert werden. Dazu gehört v. a. auch eine kritische Auseinandersetzung mit den Leitbildern, Visionen und Nutzenversprechen, mit denen technische Innovationen oft sehr absichtsvoll ausgestattet werden. Wird dabei die Distanz zur Rhetorik der Protagonisten der neuen Techniken nicht gewahrt, gerät die ethische Reflexion unvermittelt in die Rolle, profane Marketingstrategien wortgewandt und ideenreich zu veredeln. (shrink)

ZusammenfassungDie prospektive Analyse der ethischen Implikationen medizinisch-technischer Innovationen läuft immer auch Gefahr, sich in den Wunschbildern von Marketingexperten zu verfangen. Vor diesem Hintergrund könnte es durchaus nützlich sein, die Erkenntnisse der Wissenschafts- und Technikforschung zur Genese und Entwicklung neuer Techniken auszuschöpfen. Dies erscheint gerade auch für die ins Phantastische weisende Zukunft der Individualisierung medikamentöser Therapie, wie man ihr häufig in der Beschreibung pharmakogenetischer Behandlungskonzepte begegnet, angebracht. Techniken, die sich noch im Entwicklungsstadium befinden und deren breite Anwendung noch einige Jahre auf (...) sich warten lassen wird, sollten sehr sorgfältig auf ihren Realitätsgehalt und das zu erwartende Leistungspotenzial hin analysiert werden. Dazu gehört v. a. auch eine kritische Auseinandersetzung mit den Leitbildern, Visionen und Nutzenversprechen, mit denen technische Innovationen oft sehr absichtsvoll ausgestattet werden. Wird dabei die Distanz zur Rhetorik der Protagonisten der neuen Techniken nicht gewahrt, gerät die ethische Reflexion unvermittelt in die Rolle, profane Marketingstrategien wortgewandt und ideenreich zu veredeln. (shrink)

Tous les évènements traumatiques instaurent un rapport spécifique au temps. Parmi eux, le génocide constitue un paradigme de l’expérience extrême. Le génocide est un évènement qui échappe au temps commun et qui instaure une nouvelle temporalité, tant pour les victimes que pour les bourreaux. En analysant des témoignages oraux et écrits de rescapés de la Shoah et du génocide des Tutsi au Rwanda, on constate que la temporalité instaurée par le génocide continue longtemps après la fin des massacres à se (...) réverbérer sur la vie des survivants dont les familles ont été décimées. (shrink)

La nostalgie est cet état psychique qui se tient quelque part entre le deuil, la dépression et la mélancolie, avec lesquels on la confond souvent. Définie très tôt comme la maladie de l’exilé, la nostalgie est un pharmakon, à la fois baume et poison pour celui qui s’y adonne. À partir des écrits de Jean Améry, survivant de la Shoah, et de sa propre expérience auprès des survivants du génocide rwandais, l’auteur, psychanalyste, distingue ici deux positions face à la nostalgie (...) : la position nostalgique et l’évitement, toutes deux à l’origine d’états pathologiques qui peuvent conduire à la mélancolie, voire au suicide. (shrink)

During the last third of the 19th century, the ‘new’ French psychology developed within ‘the hypnotic context’ opened up by Charcot. In spite of their claims to the scientific nature of their hypnotic experiments, Charcot and his followers were unable to avoid the miracles that had accompanied mesmerism, the forerunner of hypnosis. The hysterics hypnotized in the Salpêtrière Hospital were expected to have supernormal faculties and these experiments opened the door to psychical research. In 1885 the first French psychology society (...) was founded. The research carried out by this society may seem surprising: its members – Charles Richet in particular – were interested in strange phenomena, like magnetic lucidity, ‘mental suggestion’, thought-reading, etc. Very quickly, psychologists applied themselves to finding rational explanations for these supposedly miraculous gifts. Generally, they ascribed them to unconscious or subconscious perceptual mechanisms. Finally, after a few years, studies of psychical phenomena were excluded from the field of psychology. However, during the 4th International Congress of Psychology, which took place in Paris in 1900, the foundation of an institute devoted to the study of psychical phenomena was announced, but Pierre Janet and Georges Dumas founded within it the Société Française de Psychologie, from which psychical research was excluded. As for Charles Richet, disappointed by the psychologists, he devoted himself to the development of a new ‘science’ which he called ‘Métapsychique’. Several hypotheses have been put forward to account for this early research undertaken by the French psychologists, pertaining as much to parapsychology as to scientific psychology. (shrink)

This book explores the semantic and pragmatic mechanisms underlying grammaticalization. Regine Eckardt argues that language change frequently involves a structural reorganization at the phonological, morphological, and syntactic levels. Speakers not only master the structural aspect of such reanalyses, they also-as the author argues-keep a detailed mental record of what has happened to meaning. The author develops semantic reanalysis as the semantic correlate and tracks its effects in meaning change. Several case studies offer new insights in the architecture of conceptual (...) thinking that is part of the human language faculty. Professor Eckardt develops her approach in terms of formal semantic theory. She shows how neatly tailored analyses in truth-conditional compositional semantics can elucidate the structural mechanisms of meaning change. Her exposition is advanced in the context of several in-depth case studies containing data new to historical linguistics. This book will be of central interest to scholars and advanced students of historical and comparative linguistics and of formal semantics in departments of linguistics and philosophy. (shrink)

In focusing on relations between data and vision and proposing to address big data in terms of currently dominant optical metaphors, the paper makes a case for an approach that allows for clearer distinctions between big data as ‘visions’, and data technologies. assessing notions and visions of panoptic data technologies, I outline three perspectives on the nexus between data and vision. Following Bruno Latour’s counter-image of “oligoptica”, I argue, more generally, in favour of a conceptual framework that understands big data (...) as a sociotechnical infrastructure, and discuss, drawing on more recent studies, in which ways this approach allows to address social and ethical implications of present data technologies and practices in a more differentiated way. (shrink)

ABSTRACT The first part of this article relies on a number of well-known notions drawn directly from Bakhtin's work, while bringing to bear others inspired by the Bakhtinian perspective. The second part proposes a study dealing with the diverse kinds of verbal interactions rooted in Bakhtin's notion of responsive act. These include interdiscursivity, interlocution, and intralocution, elaborated by Jacques Brès among others, as well as moves and shifts, which we owe to Frédéric François. In the third part, this body of (...) notions is tested on a corpus of verbal interactions between young children and adults, and between two or more children. The study stresses the diversity and early use of these different kinds of dialogical relations in children's language practices. It also shows how a Bakhtinian approach can contribute to research on language acquisition. (shrink)

La mesure d'audience est au coeur de l'activité des médias dits de masse: elle sert de référence pour quantifier les auditoires et s'impose comme mode de consultation du public. Le présent numéro d'Hermès présente tout d'abord les systèmes de mesure d'audience des différents médias , mettant en évidence que l'audience est le résultat d'un ensemble de contraintes et d'un consensus toujours fragile entre les partenaires concernés. La deuxième partie, plus particulièrement centrée sur la télévision généraliste, analyse les effets de la (...) concurrence sur les programmes et les programmations. La partie suivante s'interroge sur la validité de l'audience comme moyen de connaissance des publics, et sur la possibilité de créer d'autres types de liens avec le téléspectateur. Enfin, la spécificité d'Internet par rapport aux médias traditionnels permet d'affirmer que la mesure d'audience n'y jouera sans doute jamais le rôle central, un nouveau mode de relation s'instaurant avec l'usager.Audience research is at the centre of mass media activity: it serves as a reference to quantify viewers and are considered to be THE way to survey audiences. This issue of Hermes first presents different audience rating systems used by the media , emphasizing the fact that the audience is the result of many constraints and of an invariably weak consensus between the partners concerned. The second part focuses more particularly on traditional TV channels, analyses the effects of competition on schedules and programming. The section that follows questions the validity of the audience as a means of getting to know viewers and also questions the possibility of creating other types of links with the viewer. Finally, the specificity of the Internet as opposed to more "traditional" media leads us to observe that audience rating might never play a central role in this media since a new type of relations is being created with users. (shrink)

L'évolution de la mesure d'audience TV est indissociable des principales étapes qui ont mené d'une télévision publique en situation de monopole à un système mixte public/privé. Les résultats du panel postal de l'ORTF, premier dispositif fiable et permanent , sont réservés aux seuls dirigeants des chaînes, afin d'éclairer une politique de programmes encore volontariste, tandis que le CESP mène une enquête parallèle à destination de la profession publicitaire. La montée de la compétition entre chaînes publiques s'accompagne de l'attention croissante accordée (...) à l'audience et, en 1982, la mise en place de l'audimétrie-foyer représente une véritable révolution, par la rapidité et la précision des résultats obtenus. Avec l'arrivée des chaînes commerciales et la concurrence entre diffuseurs qui en résulte, les publicitaires sont en mesure d'exiger leur participation au contrôle de l'outil géré par Médiamétrie et imposent l'audimétrie individuelle , qui permet un suivi par cible.The evolution of TV audience research is indissociably linked to the main stages of television’s own history which saw it progress from a single state-owned channel with no competition to a system where public and commercial channels co-exist. Results from the ORTF postal panel set up in 1969, the first reliable and permanent measuring device, are only given to channel executives to help shed some light on a programming policy which is still volontarist. The CESP also conducts a parallel survey used by advertisers. The rise in competition between public channels has gone hand-in-hand with the growing attention paid to audience ratings and the introduction, in 1982, of rating measurement meters represented a real revolution since results are accurate and rapidly obtained. The arrival of commercial channels and the resulting competition between broadcasters meant that advertisers were able to demand a say in the control of the “Médiamétrie” audience ratings system and imposed the introduction of the TV “people meter” which permits the calculation of target audiences. (shrink)

Food security is becoming an increasingly relevant topic in the Global North, especially in urban areas. Because such areas do not always have good access to nutritionally adequate food, the question of how to supply them is an urgent priority in order to maintain a healthy population. Urban and peri-urban agriculture, as sources of local fresh food, could play an important role. Whereas some scholars do not differentiate between peri-urban and urban agriculture, seeing them as a single entity, our hypothesis (...) is that they are distinct, and that this has important consequences for food security and other issues. This has knock-on effects for food system planning and has not yet been appropriately analysed. The objectives of this study are to provide a systematic understanding of urban and peri-urban agriculture in the Global North, showing their similarities and differences, and to analyse their impact on urban food security. To this end, an extensive literature review was conducted, resulting in the identification and comparison of their spatial, ecological and socio-economic characteristics. The findings are discussed in terms of their impact on food security in relation to the four levels of the food system: food production, processing, distribution and consumption. The results show that urban and peri-urban agriculture in the Global North indeed differ in most of their characteristics and consequently also in their ability to meet the food needs of urban inhabitants. While urban agriculture still meets food needs mainly at the household level, peri-urban agriculture can provide larger quantities and has broader distribution pathways, giving it a separate status in terms of food security. Nevertheless, both possess potential, making them valuable for urban food planning, and both face similar threats regarding urbanisation pressures, necessitating adequate planning measures. (shrink)

This paper investigates the meaning of German selbst (≈ E N-self) in its intensifying use, and the relation of this selbst to the focus particle selbst (≈ E even). I propose that intensifying selbst denotes type-lifted variants of the identity function on the domain of individuals, and that the observed stress accents must be analysed in terms of by now well-established focus theories. This analysis covers the core range of data correctly, predicting obligatory stress on selbst, sortal restrictions, centrality effects, (...) and the distribution of examples that express some kind of surprise. Moreover, it allows for a treatment of the reanalysis of intensifying selbst into focus particle selbst that stipulates fewer historical accidents than previous accounts. (shrink)

Apuleius’ tale of Cupid and Psyche is shown to feature detailed knowledge of ancient magic integrated into the plot, especially the magic of the so-called ‘Sword of Dardanus’ spell and of other papyri with Middle Platonic content. A recently published gemstone from Perugia testifies to the wide distribution of the ‘Sword’. Apuleius’ allusion to the erotic spell involves both Cupid and Venus torturing Psyche. Although Venus’ intentions are to prevent the bond between the lovers, her actions inadvertently echo those depicted (...) in the ‘Sword’ and contribute to the couple's eternal union. Ancient magic is therefore shown to be potent and effective, despite Venus’ plans. This is a methodology Apuleius is known to use widely, for example in his obvious allusions to, and adaptations of, Hellenistic poetry in the story. Magic joins poetry and philosophy as a category of texts shown to be playfully integrated into Apuleius’ construction of the plot of Cupid and Psyche. (shrink)

La relation fraternelle est un domaine encore peu étudié et dont on n’épuise pas le sens et la fonction en la pensant comme n’étant qu’une projection sur les pairs d’une problématique qui se jouerait, en fait, avec les ascendants. La séduction fraternelle peut s’analyser à lueur de la problématique parents-enfants ou à celle de l’identification mentale, les deux axes pouvant, pour un même cas, se trouver intriqués de façon complexe. À partir de cas cliniques, nous montrons qu’il convient de différencier (...) ces deux axes pour mieux saisir le sens et la fonction de la séduction fraternelle dans la construction psychique du sujet, dans la naissance des conflits et dans leur résolution. La séduction fraternelle est à mi-chemin de la découverte de la différence des sexes et de la relation incestueuse, à mi-chemin des jeux sexuels infantiles et de la découverte de la sexualité génitale. En ce sens, elle constitue à la fois un miroir, un révélateur et un enjeu dans la construction du sujet en devenir. (shrink)